Fanconi anemia and ubiquitination.
Beijing, China. In J Genet Genomics, 2007
The ubiquitin E3 ligase FANCL, an important factor of FA core complex, co-functions with a new ubiquitin conjugating enzyme UBE2T to catalyze the monoubiquitination of FANCD2.
Targeting Ubc9 for cancer therapy.
Springfield, United States. In Expert Opin Ther Targets, 2005
Ubiquitin-conjugating enzyme (Ubc9) was originally thought to be a conjugating enzyme for ubiquitylation, but was later shown to be responsible for the most recently identified type of post-translational modification, (i.e., SUMO [small ubiquitin-related modifier]) conjugation or sumoylation.