PUGNAc induces protein ubiquitination in C2C12 myotube cells.
Taegu, South Korea. In Cell Biochem Funct, Dec 2015
Upregulation of proteins, including ubiquitin-activating enzyme E1, proteasome subunit 20S, cullin-associated NEDD8-dissociated protein 1, ezrin, and downregulation of the protein nucleoside diphosphate kinase B, were confirmed by western blot analysis.
Neddylation dysfunction in Alzheimer's disease.
Little Rock, United States. In J Cell Mol Med, 2012
Central to the neddylation pathway is the amyloid precursor protein (APP)-binding protein APP-BP1, which together with Uba3, plays an analogous role to the ubiquitin-activating enzyme E1 in nedd8 activation.
Structural genomics of membrane proteins.
Tokyo, Japan. In Acc Chem Res, 2003
A program on the structural genomics of membrane proteins has started at the BIRC, AIST, involving other academic institutions and industrial companies.