hnRNP A1 proofreads 3' splice site recognition by U2AF.
Barcelona, Spain. In Mol Cell, 2012
hnRNP A1 forms a ternary complex with the U2AF heterodimer on AG-containing/uridine-rich RNAs, while it displaces U2AF from non-AG-containing/uridine-rich RNAs, an activity that requires the glycine-rich domain of hnRNP A1
Multiple RNA binding domains (RBDs) just don't add up.
New Haven, United States. In Nucleic Acids Res, 1995
In the cases of heterogenous nuclear ribonucleoprotein A1 (hnRNP A1), yeast poly-A binding protein and splicing factor U2AF65, the individual free energy of binding of the RBDs for RNA are not strictly additive.