Phytosulfokine peptide signalling.
Kiel, Germany. In J Exp Bot, Aug 2015
Processing of the preproprotein involves sulfonylation by a tyrosylprotein sulfotransferase in the trans-golgi and proteolytic cleavage in the apoplast.
Genetic variation in microRNA-binding site and prognosis of patients with colorectal cancer.
Taegu, South Korea. In J Cancer Res Clin Oncol, 2015
In the validation cohort, two SNPs (TPST1 rs3757417T>G and PAUF rs12373A>C) were significantly associated with prognosis in the same direction as the discovery cohort when adjusted for age, preoperative carcinoembryonic antigen level, and pathologic stage (discovery + validation cohort; TPST1 rs3757417T>G, disease-free survival (DFS), p value = 0.0004, overall survival (OS), p value = 0.01 in recessive model; PAUF rs12373A>C, DFS, p value = <0.0001,
Fluorescent peptide sensors for tyrosylprotein sulfotransferase activity.
Minneapolis, United States. In Anal Biochem, 2014
Tyrosine sulfurylation is a post-translational modification important for protein-protein interactions in the extracellular space that are instrumental in cell adhesion, cell signaling, immune responses, and pathogen recognition of host cells.
Tyrosine sulfation and the secretory pathway.
Heidelberg, Germany. In Annu Rev Physiol, 1987
The sulfation reaction is catalyzed by tyrosylprotein sulfotransferase, an integral membrane protein that recognizes tyrosine residues in exposed protein domains containing acidic amino acids.