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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Tyrosine hydroxylase

tyrosine hydroxylase, Tyrosine 3-Monooxygenase
Top mentioned proteins: CAN, HAD, ACID, V1a, AGE
Papers using tyrosine hydroxylase antibodies
Production and purification of lentiviral vectors.
Supplier
Kahle Philipp J., In PLoS ONE, 2005
... (Wako Chemicals), mouse anti-α-syn (BD Transduction Laboratories), mouse anti-human α-syn (LB509; Invitrogen), mouse anti-β-actin, rabbit anti-tyrosine hydroxylase (anti-TH; Abcam), rabbit anti-GFP (Abcam), rabbit ...
Papers on tyrosine hydroxylase
Neuropeptide Y input to the rat basolateral amygdala complex and modulation by conditioned fear.
New
Urban et al., North Chicago, United States. In J Comp Neurol, Feb 2016
NPY innervation of the BLA was assessed in rats by examining the degree of NPY co-expression within interneurons or catecholaminergic fibers using somatostatin and tyrosine hydroxylase (TH) or dopamine β-hydroxylase (DβH), respectively.
Long-term controlled GDNF over-expression reduces dopamine transporter activity without affecting tyrosine hydroxylase expression in the rat mesostriatal system.
New
González-Hernández et al., Santa Cruz de Tenerife, Spain. In Neurobiol Dis, Feb 2016
However, studies in rodents show that prolonged GDNF over-expression may cause a tyrosine hydroxylase (TH, the limiting enzyme in DA synthesis) decline.
Differential expression of calbindin in nigral dopaminergic neurons in two mice strains with differential susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
New
Alladi et al., Bengaluru, India. In J Chem Neuroanat, Feb 2016
Calbindin-tyrosine hydroxylase immunofluorescence co-labeling was performed to map the calbindin immunoreactive DA neurons in SNpc and ventral tegmental area (VTA) and to quantify the calbindin expression at cellular level.
Retrograde Melanopsin Signaling Increases With Age in Retinal Degenerate Mice Lacking Rods and the Majority of Cones.
New
Vugler et al., London, United Kingdom. In Invest Ophthalmol Vis Sci, Feb 2016
METHODS: We used functional anatomy for c-fos (Fos) and tyrosine hydroxylase (TH) to measure light-driven activation of dopamine neurons along a dorsal-ventral transect in C3H/He wild-type and rodless-coneless rd/rd cl (rdcl) mice aged 3, 5, and >14 months.
Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.
New
Impact
Hedrick et al., Los Angeles, United States. In Nat Immunol, Dec 2015
In contrast, myeloid-specific deletion of tyrosine hydroxylase (TH), the rate-limiting enzyme in catecholamine biosynthesis, protected mice against EAE.
Structural insights into the regulation of aromatic amino acid hydroxylation.
Review
New
Fitzpatrick, San Antonio, United States. In Curr Opin Struct Biol, Dec 2015
The aromatic amino acid hydroxylases phenylalanine hydroxylase, tyrosine hydroxylase, and tryptophan hydroxylase are homotetramers, with each subunit containing a homologous catalytic domain and a divergent regulatory domain.
Acupuncture for Parkinson's Disease: a review of clinical, animal, and functional Magnetic Resonance Imaging studies.
Review
New
Xiao, In J Tradit Chin Med, Dec 2015
Animal studies have consistently show that this treatment is both neuroprotective, protecting dopaminergic neurons from degeneration and also restorative, restoring tyrosine hydroxylase positive dopaminergic terminals in striatum, resulting in improvements in motor performance in animal models of Parkinsonism.
Clinical Use of CSF Neurotransmitters.
Review
New
Pearl et al., Boston, United States. In Pediatr Neurol, Oct 2015
CONCLUSIONS: Lumbar puncture is required to detect abnormal cerebrospinal fluid metabolites in a significant proportion of these disorders, including treatable entities such as dopa-responsive deficiencies of guanosine-5'-triphosphate cyclohydrolase I (Segawa disease), sepiapterin reductase, and tyrosine hydroxylase.
A sexually dimorphic hypothalamic circuit controls maternal care and oxytocin secretion.
New
Impact
Kimchi et al., Israel. In Nature, Oct 2015
Here we show that tyrosine hydroxylase (TH)-expressing neurons in the anteroventral periventricular nucleus (AVPV) of the mouse hypothalamus are more numerous in mothers than in virgin females and males, and govern parental behaviours in a sex-specific manner.
Thyroid Paraganglioma.
Review
New
Policarpio-Nicolas et al., San Antonio, United States. In Arch Pathol Lab Med, Aug 2015
Immunohistochemical stains (cytokeratin, parathyroid hormone, thyroid transcription factor 1, tyrosine hydroxylase, chromogranin A, synaptophysin, S100, calcitonin, carcinoembryonic antigen) are essential in establishing the diagnosis.
The Retinal TNAP.
Review
Somogyvári et al., Budapest, Hungary. In Subcell Biochem, 2014
These strata exactly corresponded those seen after quadruple immunohistochemistry with four canonical IPL markers (tyrosine hydroxylase, choline acetyltransferase, calretinin, protein kinase C α). Diabetes results in diminishing retinal TNAP activity before changes in canonical markers could be observed in a rat model.
Critical genes in head and neck squamous cell carcinoma revealed by bioinformatic analysis of gene expression data.
Li et al., Hangzhou, China. In Genet Mol Res, 2014
Five PPI networks were constructed from which hub genes were acquired, such as minichromosome maintenance complex component 7 (MCM7), MCM2, decorin (DCN), retinoblastoma 1 (RB1), and tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma (YWHAG).
Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat.
Impact
Chawla et al., San Francisco, United States. In Cell, 2014
Mechanistically, macrophages recruited to cold-stressed subcutaneous white adipose tissue (scWAT) undergo alternative activation to induce tyrosine hydroxylase expression and catecholamine production, factors required for browning of scWAT.
Impact of circadian nuclear receptor REV-ERBα on midbrain dopamine production and mood regulation.
Impact
Kim et al., Seoul, South Korea. In Cell, 2014
Also, REV-ERBα repressed tyrosine hydroxylase (TH) gene transcription via competition with nuclear receptor-related 1 protein (NURR1), another nuclear receptor crucial for dopaminergic neuronal function, thereby driving circadian TH expression through a target-dependent antagonistic mechanism.
Neuroblastoma mRNAs predict outcome in children with stage 4 neuroblastoma: a European HR-NBL1/SIOPEN study.
Impact
Burchill et al., London, United Kingdom. In J Clin Oncol, 2014
METHODS: RTqPCR for paired-like homeobox 2b (PHOX2B), tyrosine hydroxylase (TH), and doublecortin (DCX) mRNA in PB and BM of children enrolled onto the High-Risk Neuroblastoma Trial-1 of the European Society of Pediatric Oncology Neuroblastoma Group (HR-NBL1/SIOPEN) was performed at diagnosis and after induction therapy.
Gender-specific regulation of tyrosine hydroxylase in thymocyte differentiation antigen-1 knockout mice.
GeneRIF
Vrana et al., United States. In J Neurosci Res, 2012
Our results suggest a gender effect on tyrosine hydroxylase (TH) specific activity, TH protein levels, and serine-40 phosphorylation of TH in Thy-1 KO female mice.
Ciliary neurotrophic factor stimulates tyrosine hydroxylase activity.
GeneRIF
Habecker et al., Portland, United States. In J Neurochem, 2012
CNTF decreased TH enzyme levels, thereby increasing the specific activity of the enzyme
Compensatory regulation of dopamine after ablation of the tyrosine hydroxylase gene in the nigrostriatal projection.
GeneRIF
Ichinose et al., Yokohama, Japan. In J Biol Chem, 2012
local regulation of TH protein amount independent of soma and trans-axonal regulation of apparent L-dihydroxyphenylalanine synthesis activity per TH protein.
Postnatal development of tyrosine hydroxylase mRNA-expressing neurons in mouse neostriatum.
GeneRIF
Aosaki et al., Tokyo, Japan. In Eur J Neurosci, 2011
Postnatal development of tyrosine hydroxylase mRNA-expressing neurons in mouse neostriatum.
Protein kinase C-dependent dephosphorylation of tyrosine hydroxylase requires the B56δ heterotrimeric form of protein phosphatase 2A.
GeneRIF
Nairn et al., Seoul, South Korea. In Plos One, 2010
activation of the B56delta-containing heterotrimeric form of PP2A is responsible for enhanced dephosphorylation of Ser40 of tyrosine hydroylase in response to stimulation of PKC
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