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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Cadherin 5

Type 2
Top mentioned proteins: Insulin, AGE, HAD, CAN, fibrillin-1
Papers on Type 2
Self-reactive IgE exacerbates interferon responses associated with autoimmunity.
New
Impact
Sanjuan et al., Gaithersburg, United States. In Nat Immunol, Feb 2016
Canonically, immunoglobulin E (IgE) mediates allergic immune responses by triggering mast cells and basophils to release histamine and type 2 helper cytokines.
EFFECT OF TOTAL DAILY DOSE ON EFFICACY, DOSING, AND SAFETY OF 2 DOSE TITRATION REGIMENS OF HUMAN REGULAR U-500 INSULIN IN SEVERELY INSULIN-RESISTANT PATIENTS WITH TYPE 2 DIABETES.
New
Jackson et al., Spokane, United States. In Endocr Pract, Feb 2016
OBJECTIVE: To examine the influence of baseline U-100 insulin total daily dose (TDD) on clinical outcomes in severely insulin-resistant patients with inadequately controlled type 2 diabetes treated with human regular U-500 insulin (U-500R) from the perspective of current dosing recommendations.
Incidence of type 1 diabetes in age groups above 15 years: facts, hypothesis and prospects for future epidemiologic research.
Review
New
Songini et al., Torino, Italy. In Acta Diabetol, Feb 2016
Paucity of registries expanding the recruitment of incident cases up to adulthood, atypical clinical features of type 1 diabetes at onset, misclassification of type 1 as type 2 diabetes and little use of markers of β-cell autoimmunity represents major obstacles in studying the risk of type 1 diabetes in adults.
Treatment intensification in patients with inadequate glycemic control on basal insulin: rationale and clinical evidence for the use of lixisenatide and other glucagon-like peptide-1 receptor agonists.
Review
New
Pozzilli et al., Bari, Italy. In Diabetes Metab Res Rev, Feb 2016
UNASSIGNED: A substantial proportion of patients with type 2 diabetes mellitus do not reach glycemic targets, despite treatment with oral antidiabetic drugs and basal insulin therapy.
WITHDRAWN: Dietary advice for the prevention of type 2 diabetes mellitus in adults.
Review
New
Moore et al., Middlesbrough, United Kingdom. In Cochrane Database Syst Rev, Feb 2016
BACKGROUND: Prevention of type 2 diabetes in adults is a far better option than treatment, to alleviate pressure on health care providers and resources.
Search for Genetic Variant in the Apelin (APLN) Gene by Resequencing and Association Study in European Subjects.
New
Baroni et al., Roma, Italy. In Genet Test Mol Biomarkers, Feb 2016
We have recently demonstrated that subjects with type 2 diabetes (T2D) have significantly higher serum apelin levels compared with controls, and that these levels associate with fasting glucose, basal disposition index, age, and diagnosis of T2D.
Tissue-specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans.
New
Das et al., Winston-Salem, United States. In J Clin Endocrinol Metab, Feb 2016
CONTEXT: Compared with European Americans, African Americans (AAs) are more insulin-resistant, have a higher insulin secretion response to glucose, and more often develop type 2 diabetes.
Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites.
New
Impact
Jay et al., Montpellier, France. In Nature, Feb 2016
The host defence against helminths such as Nippostrongylus brasiliensis is orchestrated by type 2 cell-mediated immunity.
Dramatis Personae in β-Cell Mass Regulation: Enter SerpinB1.
New
Impact
Rorsman et al., Oxford, United Kingdom. In Cell Metab, Feb 2016
The answer to this question is central to the understanding of the causes and (potentially) the therapy of type 2 diabetes.
SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination.
New
Impact
Greenblatt et al., Toronto, Canada. In Nature, Feb 2016
SMN interacts with senataxin, which is sometimes mutated in ataxia oculomotor apraxia type 2 and amyotrophic lateral sclerosis.
[Nasal Highflow (NHF): A New Therapeutic Option for the Treatment of Respiratory Failure].
New
Nilius et al., Herdecke, Germany. In Pneumologie, Jan 2016
Non-invasive or invasive positive pressure ventilation will be initiated when the oxygen therapy effects are not sufficient or if hypercapnic respiratory failure (type 2) is the underlying problem.
FGF21 Regulates Sweet and Alcohol Preference.
New
Impact
Kliewer et al., Cambridge, United States. In Cell Metab, Jan 2016
Since analogs of FGF21 are currently undergoing clinical evaluation for the treatment of obesity and type 2 diabetes, our findings raise the possibility that FGF21 administration could affect nutrient preference and other reward behaviors in humans.
Yoga for Adults with Type 2 Diabetes: A Systematic Review of Controlled Trials.
Review
New
Selfe et al., Morgantown, United States. In J Diabetes Res, Dec 2015
A growing body of evidence suggests yogic practices may benefit adults with type 2 diabetes (DM2).
Factors Motivating Individuals to Consider Genetic Testing for Type 2 Diabetes Risk Prediction.
New
de Groot et al., Indianapolis, United States. In Plos One, Dec 2015
UNASSIGNED: The purpose of this study was to identify attitudes and perceptions of willingness to participate in genetic testing for type 2 diabetes (T2D) risk prediction in the general population.
Medicinal Plants Qua Glucagon-Like Peptide-1 Secretagogue via Intestinal Nutrient Sensors.
Review
Jang et al., Seoul, South Korea. In Evid Based Complement Alternat Med, 2014
Because GLP-1 is rapidly inactivated by the enzymatic cleavage of dipeptidyl peptidase-4 (DPP4) long-acting GLP-1 analogues, for example, exenatide and DPP4 inhibitors, for example, liraglutide, have been developed as therapeutics for type 2 diabetes mellitus (T2DM).
Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis.
GeneRIF
Essner et al., Ames, United States. In Development, 2010
suggest that Ve-cadherin and Moesin1 function to establish and maintain apical/basal polarity during multicellular lumen formation in the intersegmental vessels
Effect of vascular cadherin knockdown on zebrafish vasculature during development.
GeneRIF
Nwariaku et al., Dallas, United States. In Plos One, 2009
results demonstrate a significant role for VE-cadherin in cardiac development independent of its effects on the formation of the peripheral vasculature
Stable vascular connections and remodeling require full expression of VE-cadherin in zebrafish embryos.
GeneRIF
Dejana et al., Milano, Italy. In Plos One, 2008
VE-cadherin plays an essential role in vascular development
Genome-wide analysis of the zebrafish ETS family identifies three genes required for hemangioblast differentiation or angiogenesis.
GeneRIF
Patient et al., Oxford, United Kingdom. In Circ Res, 2008
fli1, and etsrp, demonstrated that erg and fli1 act cooperatively and are required for angiogenesis possibly via direct regulation of an endothelial cell junction molecule, VE-cadherin
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