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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Thioredoxin-like 1

TXL, Trp32
Top mentioned proteins: V1a, CAN, ACID, Thioredoxin, HAD
Papers on TXL
Thioredoxin-like protein 2b facilitates colon cancer cell proliferation and inhibits apoptosis via NF-κB pathway.
Fan et al., Xi'an, China. In Cancer Lett, Aug 2015
Our previous work identified thioredoxin-like protein 2 (Txl-2), a novel thioredoxin family member, as the target of the monoclonal antibody MC3 which can detect colon cancer with high sensitivity and specificity.
Tongxinluo Induces nNOS Expression Through ERK Activation: Possible Contribution to the Effects of Tongxinluo to Attenuate Vasoconstriction.
Zeng et al., Shenyang, China. In J Cardiovasc Pharmacol, Jul 2015
In this study, we intended to investigate the possible role of nNOS in mediating the effect of Chinese medicine Tongxinluo (TXL) to attenuate vasoconstriction induced by the chronic injury in the collared carotid artery.
Tongxinluo (TXL), a Traditional Chinese Medicinal Compound, Improves Endothelial Function After Chronic Hypoxia Both In Vivo and In Vitro.
Zheng et al., Shijiazhuang, China. In J Cardiovasc Pharmacol, Jun 2015
The aim of this study was to investigate whether the endothelial protection conferred by tongxinluo (TXL), a traditional Chinese medicinal compound, is related to its regulation of TJ protein expression.
Chinese medicine Tongxinluo increases tight junction protein levels by inducing KLF5 expression in microvascular endothelial cells.
Wen et al., Shijiazhuang, China. In Cell Biochem Funct, Jun 2015
Tongxinluo (TXL) is a compound prescription formulated according to the meridian theory of traditional Chinese medicine.
Tongxinluo inhibits cyclooxygenase-2, inducible nitric oxide synthase, hypoxia-inducible factor-2α/vascular endothelial growth factor to antagonize injury in hypoxia-stimulated cardiac microvascular endothelial cells.
Tian et al., Shijiazhuang, China. In Chin Med J (engl), May 2015
Whether and how Tongxinluo (TXL) modulates COX-2, PGIS, iNOS, eNOS, HIF-1α, HIF-2α, and VEGF in Hx-stimulated human cardiac microvascular endothelial cells (HCMECs) have not been clarified.
Jadomycin breast cancer cytotoxicity is mediated by a copper-dependent, reactive oxygen species-inducing mechanism.
Goralski et al., Halifax, Canada. In Pharmacol Res Perspect, Mar 2015
The objective of this study was to determine if and how ROS contribute to jadomycin cytotoxicity in drug-sensitive MCF7 (MCF7-CON) and taxol-resistant MCF7 (MCF7-TXL) breast cancer cells.
Effect of Tongxinluo on Nephrin Expression via Inhibition of Notch1/Snail Pathway in Diabetic Rats.
Wang et al., Beijing, China. In Evid Based Complement Alternat Med, 2014
Moreover, it has been demonstrated that tongxinluo (TXL) can ameliorate renal structure disruption and dysfunction in DN.
Chinese medicine Tongxinluo reduces atherosclerotic lesion by attenuating oxidative stress and inflammation in microvascular endothelial cells.
Wen et al., Shijiazhuang, China. In Int J Clin Exp Pathol, 2014
The aim of present study was to investigate whether anti-atherosclerotic effect of Tongxinluo (TXL), a compound traditional Chinese medicine, is related to its anti-oxidation and anti-inflammation in human cardiac microvascular endothelial cells (HCMEC).
Cardiac microvascular barrier function mediates the protection of Tongxinluo against myocardial ischemia/reperfusion injury.
Yang et al., Beijing, China. In Plos One, 2014
OBJECTIVE: Tongxinluo (TXL) has been shown to decrease myocardial necrosis after ischemia/reperfusion (I/R) by simulating ischemia preconditioning (IPC).
Effects of tongxinluo on the neointima formation and expression of inflammatory cytokines in rats after carotid artery balloon injury.
Xu et al., Fuzhou, China. In Indian J Pharmacol, 2014
OBJECTIVE: Tongxinluo (TXL) is a traditional Chinese medicine (TCM).
Tongxinluo inhibits vascular inflammation and neointimal hyperplasia through blockade of the positive feedback loop between miR-155 and TNF-α.
Wen et al., In Am J Physiol Heart Circ Physiol, 2014
Tongxinluo (TXL), a traditional Chinese medicine, has multiple vasoprotective effects, including anti-inflammation.
Tongxinluo protects against pressure overload-induced heart failure in mice involving VEGF/Akt/eNOS pathway activation.
Zhao et al., Jinan, China. In Plos One, 2013
BACKGROUND: It has been demonstrated that Tongxinluo (TXL), a traditional Chinese medicine compound, improves ischemic heart disease in animal models via vascular endothelial growth factor (VEGF) and endothelial nitric oxide synthase (eNOS).
Effects of Chinese Medicine Tong xinluo on Diabetic Nephropathy via Inhibiting TGF- β 1-Induced Epithelial-to-Mesenchymal Transition.
Zhang et al., Beijing, China. In Evid Based Complement Alternat Med, 2013
Tong xinluo (TXL), a Chinese herbal compound, has been used in China with established therapeutic efficacy in patients with DN.
HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.
Habermann et al., Stockholm, Sweden. In Cell Mol Life Sci, 2011
Distinct protein expression patterns, affecting TXNL1 and HDAC2, distinguish aneuploid with poor prognosis from diploid colorectal cancers.
Solution structure of the C-terminal DUF1000 domain of the human thioredoxin-like 1 protein.
Yokoyama et al., Yokohama, Japan. In Proteins, 2010
Solution structure of the C-terminal DUF1000 domain of the human thioredoxin-like 1 protein.
Thioredoxin Txnl1/TRP32 is a redox-active cofactor of the 26 S proteasome.
Hartmann-Petersen et al., Copenhagen, Denmark. In J Biol Chem, 2009
Txnl1 is the first example of a direct connection between protein reduction and proteolysis, two major intracellular protein quality control mechanisms.
Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle.
Ron et al., New York City, United States. In J Biol Chem, 2009
TRP32 was identified as a novel subunit of the 26 S proteasome.
The redox sensor TXNL1 plays a regulatory role in fluid phase endocytosis.
Gruenberg et al., Genève, Switzerland. In Plos One, 2006
TXNL1 acts as an effector of oxidants or a redox sensor by converting redox changes into changes of GDI capacity to capture Rab5, which in turn modulates fluid phase endocytosis
The mammalian testis-specific thioredoxin system.
Oko et al., Huddinge, Sweden. In Antioxid Redox Signal, 2004
In this review, we will focus on the mammalian testis-specific thioredoxin system that comprises three thioredoxins exclusively expressed in spermatids (named Sptrx-1, Sptrx-2, and Sptrx-3) and an additional thioredoxin highly expressed in testis, but also present in lung and other ciliated tissues (Txl-2).
Hepatic chemoembolization: clinical and experimental correlation.
Li et al., Houston, United States. In Acta Gastroenterol Belg, 2000
PG-TXL, have considerable potential for intra-arterial delivery especially with the dramatic increase in concentration of the drug in the tumor and its efficacy.
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