Paris, France. In Am J Pathol, 30 Apr 2015
This Correspondence is a Reply to Lack of Evidence that HACE1 Is Not a Tumor Suppressor Gene in Natural Killer/T-Cell Lymphoma by Küçük et al.
Emerging therapeutic targets in bladder cancer.
United States. In Cancer Treat Rev, 28 Feb 2015
mTOR inhibitors for patients with TSC1 mutations and concomitant targeting of PI3K and MEK represent strategies to block PI3K/AKT/mTOR pathway.
Coordinated regulation of protein synthesis and degradation by mTORC1.
Boston, United States. In Nature, Oct 2014
Genetic activation of mTORC1 through loss of the tuberous sclerosis complex tumour suppressors, TSC1 or TSC2, or physiological activation of mTORC1 in response to growth factors or feeding resulted in increased NRF1 expression in cells and tissues.
Molecular genetics of clear-cell renal cell carcinoma.
Dallas, United States. In J Clin Oncol, Jul 2014
Several additional tumor suppressor genes have been identified near the VHL gene, within a region that is frequently deleted in ccRCC on chromosome 3p: SETD2, BAP1, and PBRM1.