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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Tubulin, beta 6 class V

Top mentioned proteins: beta-4, Tubb4, CAN, M40, Tubb2c
Papers on TUBB6
Whole genome and transcriptome sequencing of matched primary and peritoneal metastatic gastric carcinoma.
Yu et al., Shanghai, China. In Sci Rep, 2014
We identified 27 mutated genes, of which 19 genes are reported in COSMIC database (ZNF208, CRNN, ATXN3, DCTN1, RP1L1, PRB4, PRB1, MUC4, HS6ST3, MUC17, JAM2, ITGAD, IREB2, IQUB, CORO1B, CCDC121, AKAP2, ACAN and ACADL), and eight genes have not previously been described in gastric cancer (CCDC178, ARMC4, TUBB6, PLIN4, PKLR, PDZD2, DMBT1and DAB1).Additionally,GPX4 and MPND in 19q13.3-13.4
The marriage of quantitative genetics and cell biology: a novel screening approach reveals people have genetically encoded variation in microtubule stability.
Jaslow et al., Durham, United States. In Bioarchitecture, 2014
A single nucleotide polymorphism (SNP) near the TUBB6 gene, encoding class V β-tubulin, is associated with the expression level of this protein, which reduces microtubule stability at higher levels of expression.
A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation.
Harvey et al., London, United Kingdom. In J Biol Chem, 2014
LRRK2 selectively interacts with three β-tubulin isoforms: TUBB, TUBB4, and TUBB6, one of which (TUBB4) is mutated in the movement disorder dystonia type 4 (DYT4).
A cellular genome-wide association study reveals human variation in microtubule stability and a role in inflammatory cell death.
Ko et al., Seattle, United States. In Mol Biol Cell, 2014
An intergenic single-nucleotide polymorphism on chromosome 18 is associated with decreased pyroptosis and increased expression of TUBB6 (tubulin, β 6 class V).
Identification of candidate oncogenes in human colorectal cancers with microsatellite instability.
Aaltonen et al., Helsinki, Finland. In Gastroenterology, 2013
Potential mutation hot spots were confirmed in 15 genes; ADAR, DCAF12L2, GLT1D1, ITGA7, MAP1B, MRGPRX4, PSRC1, RANBP2, RPS6KL1, SNCAIP, TCEAL6, TUBB6, WBP5, VEGFB, and ZBTB2; these were validated in 86 tumors with microsatellite instability.
Gender influences the class III and V β-tubulin ability to predict poor outcome in colorectal cancer.
Ferlini et al., Danbury, United States. In Clin Cancer Res, 2012
in colorectal cancer patients, there was a link between poor survival, the expression of TUBB3/TUBB6, and androgen receptor only in females
Tumoral and tissue-specific expression of the major human beta-tubulin isotypes.
Rodríguez-Antona et al., Madrid, Spain. In Cytoskeleton (hoboken), 2010
The TUBB6 expression was largely decreased in most tumors.
A minor beta-tubulin essential for mammalian cell proliferation.
Cabral et al., Houston, United States. In Cell Motil Cytoskeleton, 2008
The results provide the first evidence that a specific isoform of beta-tubulin is required for mitosis.[beta5 tubulin]
A syndromic form of autosomal recessive congenital microcephaly (Jawad syndrome) maps to chromosome 18p11.22-q11.2.
Ahmad et al., Islamabad, Pakistan. In Hum Genet, 2008
Six candidate genes, CEP76, ESCO1, SEH1L, TUBB6, ZNF519, and PTPN2 were sequenced, and were found to be negative for functional sequence variants.
Expression profiling reveals dysregulation of cellular cytoskeletal genes in HBx-induced hepatocarcinogenesis.
Yang et al., Beijing, China. In Cancer Biol Ther, 2007
Among them, cytoskeletal genes, including microtubule genes tubulinbeta2 (Tubb2), tubulinbeta3 (Tubb3) and tubulinbeta6 (Tubb6), intermediate filament genes periplakin, keratin 8 (K8) and keratin 18 (K18) and actingamma1 (Actg1), were closely clustered and upregulated in liver tissues.
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