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Tetratricopeptide repeat domain 4

TTC4, L62
This gene encodes a protein that contains tetratricopeptide (TPR) repeats. The 34-amino acid tetratricopeptide repeat motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity.[provided by RefSeq, Jun 2011] (from NCBI)
Papers on TTC4
Nuclear transport of protein TTC4 depends on the cell cycle.
Pestov et al., Moscow, Russia. In Cell Tissue Res, 2009
The nuclear transport of TTC4 is apparently a complex process dependent on interactions with other proteins during the progression of the cell cycle.
The human TPR protein TTC4 is a putative Hsp90 co-chaperone which interacts with CDC6 and shows alterations in transformed cells.
Cotterill et al., London, United Kingdom. In Plos One, 2007
TTC4 is highly expressed in malignant melanoma
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