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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Tetratricopeptide repeat domain 12

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Top mentioned proteins: ANKK1, DRD2, HAD, Armadillo, V1a
Papers on TTC12
An initial investigation of associations between dopamine-linked genetic variation and smoking motives in African Americans.
MacKillop et al., Boulder, United States. In Pharmacol Biochem Behav, Nov 2015
Associations among haplotypes in the NCAM1-TTC12-ANKK1-DRD2 gene cluster, a dopamine-related gene region associated with ND, PDM intermediate phenotypes, and ND were examined.
NCAM1-TTC12-ANKK1-DRD2 gene cluster and the clinical and genetic heterogeneity of adults with ADHD.
Bau et al., Porto Alegre, Brazil. In Am J Med Genet B Neuropsychiatr Genet, Jun 2015
These two genes, together with NCAM1 and TTC12, form the NTAD gene cluster on Chr11q22-23.
NCAM1-TTC12-ANKK1-DRD2 variants and smoking motives as intermediate phenotypes for nicotine dependence.
MacKillop et al., Providence, United States. In Psychopharmacology (berl), Apr 2015
Based on prior evidence of the role of genetic variation in the NCAM1-TTC12-ANKK1-DRD2 region on chromosome 11q23 in smoking behavior, associations among 12 region loci with nicotine dependence and PDM phenotypes were examined using haplotype and individual loci approaches.
ANKK1, TTC12, and NCAM1 polymorphisms and heroin dependence: importance of considering drug exposure.
Montgomery et al., Saint Louis, United States. In Jama Psychiatry, 2013
OBJECTIVE: To examine association of 1430 candidate gene single-nucleotide polymorphisms (SNPs) with heroin dependence, reporting here only the 71 SNPs in the chromosome 11 gene cluster (NCAM1, TTC12, ANKK1, DRD2) that include the strongest observed associations.
Linking dopamine neurotransmission and neurogenesis: The evolutionary history of the NTAD (NCAM1-TTC12-ANKK1-DRD2) gene cluster.
Bau et al., Porto Alegre, Brazil. In Genet Mol Biol, 2012
Further research has shown a conjoined effect of genes in the Chr11q22-23 region, which includes the NCAM1, TTC12, ANKK1 and DRD2 genes, or NTAD cluster.
The role of ANKK1 and TTC12 genes on drinking behaviour in tobacco dependent subjects.
Kennedy et al., Toronto, Canada. In World J Biol Psychiatry, 2012
Our aim was to investigate whether drinking behaviour in the past 12 months and smoking relapse due to alcohol use in TD subjects was associated with polymorphisms flanking the TTC12/ANKK1/DRD2 region since associations have been found between these genes and AUD and TD as separate disorders.
Association of DRD2 and DRD3 polymorphisms with Parkinson's disease in a multiethnic consortium.
Nelson et al., Stanford, United States. In J Neurol Sci, 2011
CONCLUSIONS: DRD2 polymorphisms are unlikely to be true disease-causing variants; however, three DRD2 polymorphisms (including Taq1A) may be in linkage disequilibrium with possible disease associated variants in the DRD2-ANKK1-NCAM1-TTC12 gene cluster.
TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood.
Järvelin et al., London, United Kingdom. In Biol Psychiatry, 2011
TTC12-ANKK1-DRD2s seemed to influence smoking behavior mainly in adolescence, and its effect is partially mediated by personality characteristics promoting drug-seeking behavior.
Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans.
Eaton et al., Stanford, United States. In Nicotine Tob Res, 2010
This study evaluated the interaction of ANKK1, TTC12, sex, and continental ancestry in tobacco smokers.
Influence of DRD2 and ANKK1 genotypes on apomorphine-induced growth hormone (GH) response in alcohol-dependent patients.
Bieńkowski et al., Greifswald, Germany. In Prog Neuropsychopharmacol Biol Psychiatry, 2010
METHODS: Apomorphine challenge tests measuring GH responses on 5 time points were performed on day 1 of alcohol detoxification in 43 patients with alcohol dependence; patients were genotyped for 11 polymorphisms including DRD2, ANKK1, NCAM1 and TTC12.
Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence.
Gelernter et al., New Haven, United States. In Alcohol Clin Exp Res, 2008
Genetic linkage tests conclude that variants in TTC12 exon 3 are involved in the regulation of risk for comorbid alcohol and drug dependence.
In vivo differentiation and genomic evolution in adult male germ cell tumors.
Chaganti et al., New York City, United States. In Genes Chromosomes Cancer, 2008
Parallel expression profiling of these tumors identified potential oncogenes from gained regions (LYN and RAB25) and potential tumor suppressor genes in regions of loss (SYNPO2, TTC12, IGSF4, and EPB41L3).
Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples.
Gelernter et al., New Haven, United States. In Hum Mol Genet, 2008
association studies of alcohol dependence and 43 SNPs mapped to the gene cluster of NCAM1, TTC12, ANKK1 and DRD2
Hypermethylation of TTC12 gene in acute lymphoblastic leukemia.
Mutirangura et al., In Leukemia, 2007
the TTC12 gene is hypermethylated in acute lymphoblastic leukemia
Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations.
Farrer et al., West Haven, United States. In Hum Mol Genet, 2007
Previously, we identified a modest linkage peak (LOD score =1.97) for ND in the EA part of the sample on chromosome 11q23, a region that includes the NCAM1-TTC12-ANKK1-DRD2 gene cluster.
Identification and characterization of human FOXN5 and rat Foxn5 genes in silico.
Katoh et al., Narashino, Japan. In Int J Oncol, 2004
FOXN5 is a candidate tumor suppressor gene (TSG), just like ARHGAP20 (KIAA1391), BTG4, SNF1LK2 (SIK2), DIXDC1 (KIAA1735) genes at 11q23.1, TTC12 (TPARM) gene at 11q23.2, IGSF4, DSCAML1, LL5A (PHLDB1), BCL9L, RNF26, and MFRP genes at 11q23.3.
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