Revisiting the role of the mast cell in asthma.
Lund, Sweden. In Curr Opin Pulm Med, Jan 2016
RECENT FINDINGS: The heterogeneity of human mast cells has been recognized: MCTC expressing both tryptase and chymase and MCT expressing tryptase only.
An unusual tumour of the lung.
In Pathologica, Mar 2015
The neoplastic mast cells stained strongly with tryptase, CD117, CD68 and CD45, CD14 and CD33; whereas the undifferentiated cells lacked all these markers and expressed EMA and cytokeratin.
Mast-cell infiltration of airway smooth muscle in asthma.
Leicester, United Kingdom. In N Engl J Med, 2002
By contrast, the number of tryptase-positive mast cells in the bundles of airway smooth muscle from subjects with asthma (median, 5.1 mast cells per square millimeter of smooth muscle [range, 0 to 33.3]) was substantially higher than that in subjects with eosinophilic bronchitis (median, 0 mast cells per square millimeter; range, 0 to 4.8) and that in normal controls (median, 0 mast cells per square millimeter [range, 0 to 6.4]; P<0.001 for the comparison among the three groups).