TRPM7 and its role in neurodegenerative diseases.
Grand Forks, United States. In Channels (austin), Oct 2015
In the present review we focus on the emerging role of transient potential melastatin-7 (TRPM7) channel in not only regulating Ca(2+) and Mg(2+) homeostasis necessary for biological functions, but also how alterations in TRPM7 function/expression could induce neurodegeneration.
TRPM channels and magnesium in early embryonic development.
United States. In Int J Dev Biol, 2014
Recent studies have continued to add to the growing number of Mg (2+)transporters and ion channels involved in Mg (2+)homeostasis, including TRPM6 and TRPM7, members of the transient receptor potential (TRP) ion channel family.
Calcium flickers steer cell migration.
Beijing, China. In Nature, 2009
Calcium flicker activity is dually coupled to membrane tension (by means of TRPM7, a stretch-activated Ca(2+)-permeant channel of the transient receptor potential superfamily) and chemoattractant signal transduction (by means of type 2 inositol-1,4,5-trisphosphate receptors).