Brain transient receptor potential channels and stroke.
Singapore, Singapore. In J Neurosci Res, Aug 2015
In stroke, TRPC3/4/6, TRPM2/4/7, and TRPV1/3/4 channels have been found to participate in ischemia-induced cell death, whereas other TRP channels, in particular those expressed in nonneuronal cells, have been less well studied.
Psychiatric Disorders and TRP Channels: Focus on Psychotropic Drugs.
Isparta, Turkey. In Curr Neuropharmacol, 2014
Intracellular calcium influx induced by oxidative stress has an significant role in the etiology of bipolar disorders (BDs), and studies recently reported the important role of TRP channels such as TRPC3, TRPM2, and TRPV1 in converting oxidant or nitrogen radical signaling to cytosolic calcium ion homeostasis in BDs.
TRPs in hearing.
Göttingen, Germany. In Handb Exp Pharmacol, 2013
In vertebrates, TRPs are unlikely to form auditory transduction channels, yet most TRPs are expressed in inner ear tissues, and mutations in TRPN1, TRPVA1, TRPML3, TRPV4, and TRPC3/TRPC6 have been implicated in inner ear function.