Dependence receptors and colorectal cancer.
Lyon, France. In Gut, Nov 2014
This review will describe how receptors such as deleted in colorectal carcinoma (DCC), uncoordinated 5 (UNC5), rearranged during transfection (RET) or TrkC constrain CRC progression and how this dependence receptor paradigm may open up therapeutical perspectives.
NGF, BDNF, NT3, and NT4.
Seattle, United States. In Handb Exp Pharmacol, 2013
Four neurotrophins, NGF, brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT3), and neurotrophin-4 (NT4), regulate a wide variety of neural functions, acting upon p75NTR, TrkA, TrkB, and TrkC receptors.