GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Dec 2016.
Tripartite motif containing 15
TRIM15
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] (from
NCBI)
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Papers on
TRIM15
Role of the focal adhesion protein TRIM15 in colon cancer development.
New
South Korea. In Biochim Biophys Acta, Feb 2015
Here, we show that TRIM15 co-localized to focal adhesions through homo-dimerization and significantly suppressed cell migration.
Excess of homozygosity in the major histocompatibility complex in schizophrenia.
United States. In Hum Mol Genet, 2014
The strongest case-control recessive effects (P = 8.81 × 10(-8)) were localized to a 53-kb region near HLA-A, in a segment encompassing three poorly annotated genes, TRIM10, TRIM15 and TRIM40.
TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly.
New Haven, United States. In J Cell Sci, 2014
Here, we identify TRIM15, a member of the tripartite motif protein family, as a paxillin-interacting factor and a component of focal adhesions.
Analysis of DNA methylation patterns associated with the gastric cancer genome.
Wuhan, China. In Oncol Lett, 2014
TRIM15, ITGAM, MSX2 and FAM38A may be candidate genes for diagnosing gastric cancer.
TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.
New Haven, United States. In J Virol, 2013
We also discovered a role for TRIM15 in the RIG-I-mediated interferon pathway upstream of MAVS.
Analysis of Genome-Wide Association Study (GWAS) data looking for replicating signals in Alzheimer's disease (AD).
Nottingham, United Kingdom. In Int J Mol Epidemiol Genet, 2009
This revealed only a single SNP (rs929156 in the tripartite motif-containing protein 15, TRIM15, gene) that was replicating across all studies at a level approaching genome-wide significance (P = 8.77×10(-8)) and where meta-analysis of odds ratios showed a significant effect on risk (OR 1.1, 95% Cl 1.0-1.2,
TRIM E3 ligases interfere with early and late stages of the retroviral life cycle.
GeneRIF
New Haven, United States. In Plos Pathog, 2008
Downregulation of TRIM11 and TRIM15 enhanced virus release suggesting that these proteins contribute to the endogenous restriction of retroviruses in cells.
Genomic sequence analysis of the 238-kb swine segment with a cluster of TRIM and olfactory receptor genes located, but with no class I genes, at the distal end of the SLA class I region.
Isehara, Japan. In Immunogenetics, 2005
To complete the genomic sequence of the entire SLA class I genomic region, we have analyzed the genomic sequences of two BAC clones carrying a continuous 237,633-bp-long segment spanning from the TRIM15 gene to the UBD gene located on the telomeric side of the classical SLA class I gene cluster.
