Reboreda et al., Vigo, Spain. In Eur J Neurosci, Jul 2015
Here, we report the presence of a riluzole-activated current (IRIL ) that flows through the TREK-2 channels, and that is also inhibited by muscarinic agonists in neurons of the mouse superior cervical ganglion (mSCG).
Veale et al., Chatham, United Kingdom. In Pflugers Arch, May 2015
Expression of several different K2P channel subunits has been detected in nociceptive dorsal root ganglion neurons and trigeminal ganglion neurons, in particular, TREK1, TREK2, TRESK, TRAAK, TASK3 and TWIK1 channels.
Stucky et al., Milwaukee, United States. In Pain, 2014
These included the transient receptor potential melastatin 8 (Trpm8) and transient receptor potential ankyrin 1 (Trpa1) channels, as well as the 2-pore domain potassium channels, TREK-1 (Kcnk2), TREK-2 (Kcnk10), and TRAAK (Kcnk4).
Wickman et al., Minneapolis, United States. In Neuroscience, 2011
Two novel splice isoforms of Trek2 are characterized, both showing prominent expression in the central nervous system and suggesting a potential role for Trek2 amino terminus in channel trafficking and/or stability.
Han et al., Chinju, South Korea. In Acta Physiol (oxf), 2011
These results suggest that baicalein- and wogonin-induced TREK-2 activation help set the resting membrane potential of cells exposed to pathological conditions and thus may give beneficial effects in neuroprotection.