Mediator kinase module and human tumorigenesis.
San Antonio, United States. In Crit Rev Biochem Mol Biol, 2014
In humans, MED13, MED12, CDK8 and Cyclin C (CycC) comprise a four-subunit "kinase" module that exists in variable association with a 26-subunit Mediator core.
The roles of mediator complex in cardiovascular diseases.
Napoli, Italy. In Biochim Biophys Acta, 2014
Nowadays, also MED13 and MED15 have been associated with human congenital heart diseases and others could be added, like MED12 that is involved in early mouse development and heart formation.