Conformational Flexibility in the Transmembrane Protein TSPO.
Göttingen, Germany. In Chemistry, Dec 2015
The translocator protein (TSPO) is an integral membrane protein that interacts with a wide variety of endogenous ligands, such as cholesterol and porphyrins, and is also the target for several small molecules with substantial in vivo efficacy.
CLPTM1L polymorphism and lung cancer risk.
Wuxi, China. In Int J Clin Exp Med, 2014
The association of Cleft Lip and Palate Transmembrane Protein 1 (CLPTM1L) rs31489 polymorphism with risk of lung cancer has been evaluated in many studies; however, the results from these studies are controversial.
Structure-functional intimacies of transient receptor potential channels.
Valparaíso, Chile. In Q Rev Biophys, 2009
TRP channels constitute a large superfamily of ion channels, and can be grouped into seven subfamilies based on their amino acid sequence homology: the canonical or classic TRPs, the vanilloid receptor TRPs, the melastatin or long TRPs, ankyrin (whose only member is the transmembrane protein 1 [TRPA1]), TRPN after the nonmechanoreceptor potential C (nonpC), and the more distant cousins, the polycystins and mucolipins.