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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 02 Oct 2014.


This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009] (from NCBI)
Top mentioned proteins: HAD, CAN, Serum albumin, ACID, AGE
Papers using Transferrin antibodies
Receptor-mediated endocytosis involves tyrosine phosphorylation of cortactin
Oro Anthony E. et al., In The Journal of Cell Biology, 2006
... Endocytosis was measured using HRP-conjugated mouse Transferrin (Tfn; Sigma-Aldrich) and detected using a Sensolyte ADHP HRP ELISA Assay kit (AnaSpec).
Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade.
Signoret Nathalie, In PLoS ONE, 2005
... Manassas, VA) were grown as a monolayer in DMEM media supplemented with 5% FBS (Hyclone), 0.1% Insulin-Transferrin-Selenium (ITS) and 1% Penicillin/Streptomycin (BD Biosciences, San Jose, CA), in ...
Dynamics of protein binding to telomeres in living cells: implications for telomere structure and function
Ouellette Michel M. et al., In Nucleic Acids Research, 2003
... Fetal bovine serum, Transferrin and Microcystin-LR were from HyClone (Logan, UT, USA), Collaborative Biomedical Products (Bedford, MA, USA) ...
Compartmentalization of integrin α6β4 signaling in lipid rafts
Giancotti Filippo G. et al., In The Journal of Cell Biology, 1997
... Src SRC2, anti-caveolin-1 N-20, and anti-β4 C-20 and N-20), Transduction Laboratories (anti-Yes mAb), Zymed Laboratories (anti-Transferrin mAb), BD Biosciences (anti-tubulin mAb), CHEMICON International ...
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
Chang Yung-Fu, In PLoS ONE, 1994
... mix (1∶1) supplemented with 5% Fetal Bovine Serum, 5 ng/ml Epidermal Growth Factor (Sigma-Aldrich) and 5 ng/ml Insulin-Transferrin-Selenium mixture (BD Biosciences) without antibiotics at 37°C ...
Papers on Transferrin
A Phase III, randomized, open-label trial of ferumoxytol compared with iron sucrose for the treatment of iron deficiency anemia in patients with a history of unsatisfactory oral iron therapy.
Allen et al., Adelaide, Australia. In Am J Hematol, Jun 2014
Transferrin saturation, quality-of-life measures, and safety outcomes were similar between the two treatment groups.
A78: urine biomarkers role in predicting the future development of renal functional loss with lupus nephritis in children and adults.
Rovin et al., Cincinnati, United States. In Arthritis Rheumatol, Mar 2014
The biomarker candidates studies were liver-type fatty acid binding protein (L-FABP), albumin (Alb), monocyte chemoattractant protein 1 (MCP-1), Uromodulin, Transferrin and Hepcidin.
Characterization of carp seminal plasma proteome in relation to blood plasma.
Ciereszko et al., Olsztyn, Poland. In J Proteomics, Mar 2014
Transferrin, serine proteinase inhibitors, apolipoproteins, complement C3 and Wap65 were present in high abundance in carp seminal plasma.
Biocompatible and highly luminescent near-infrared CuInS₂/ZnS quantum dots embedded silica beads for cancer cell imaging.
Han et al., Wuhan, China. In Acs Appl Mater Interfaces, Mar 2014
Also, the functionalized CuInS2/ZnS QDs encapsulated in the silica spheres, expedited their bioconjugation with holo-Transferrin (Tf) for further cancer cell imaging.
Human Bone Marrow Mesenchymal Stem Cell Behaviors on PCL/Gelatin Nanofibrous Scaffolds Modified with A Collagen IV-Derived RGD-Containing Peptide.
Massumi et al., Tehrān, Iran. In Cell J, Mar 2014
In addition, cell adhesion and proliferation behaviors of hBMSCs on native and peptide modified scaffolds were evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and 4',6-diamidino-2-phenylindole (DAPI) staining, and the results compared with tissue culture plate, as the control.
Degeneration modulates retinal response to transient exogenous oxidative injury.
Chowers et al., Jerusalem, Israel. In Plos One, Dec 2013
At baseline, prior to PQ injection, mRNA levels of antioxidant genes (Superoxide Dismutase1, Glutathione Peroxidase1, Catalase) and of Transferrin measured by quantitative PCR were 2.1-7.8-fold
Variability of the transferrin receptor 2 gene in AMD.
Szaflik et al., Łódź, Poland. In Dis Markers, Dec 2013
Transferrin receptor 2 plays a critical role in iron homeostasis and variability in its gene may influence oxidative stress and AMD occurrence.
Molecular dynamics simulations of iron- and aluminum-loaded serum transferrin: protonation of Tyr188 is necessary to prompt metal release.
Lopez et al., San Sebastián, Spain. In Biochemistry, 2012
The study demonstrates for the first time that the protonation of Tyr188 is required for the release of metal from iron- and aluminum-loaded serum transferrin.
The immunobiology of apotransferrin in type 1 diabetes.
Nicoletti et al., Catania, Italy. In Clin Exp Immunol, 2012
Patients with newly diagnosed type 1 diabetes have lower apoTf serum levels than healthy controls & patients with long-lasting disease. apoTf has a pivotal role in the perpetuation of type 1 diabetes pathology.
Involvement of multiple distinct Bordetella receptor proteins in the utilization of iron liberated from transferrin by host catecholamine stress hormones.
Suhadolc et al., Minneapolis, United States. In Mol Microbiol, 2012
BfrA, BfrD and BfrE are catecholamine receptors and are involved in the utilization of iron liberated from transferrin by host catecholamine stress hormones.
Transferrin as a model system for method development to study structure, dynamics and interactions of metalloproteins using mass spectrometry.
Gumerov et al., Amherst Center, United States. In Biochim Biophys Acta, 2012
BACKGROUND: Transferrin (Tf) is a paradigmatic metalloprotein, which has been extensively studied in the past and still is a focal point of numerous investigation efforts owing to its unique role in iron homeostasis and enormous promise as a component of a wide range of therapies.
The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice.
Watanabe et al., Nara, Japan. In Plos One, 2011
These results indicate that CALM is required for erythroid maturation and transferrin internalization in mice.
ApoTransferrin: dual role on adult subventricular zone-derived neurospheres.
Pasquini et al., Buenos Aires, Argentina. In Plos One, 2011
This evidence supports a key role of Tf on the generation of oligodendrocytes (OLs) from Neural stem and progenitor cells (NSC/NPCs)and highlights its potential in demyelinating disorder treatment.
The impact of mass spectrometry in the diagnosis of congenital disorders of glycosylation.
Garozzo et al., Catania, Italy. In J Inherit Metab Dis, 2011
Electrospray (ESI) MS and matrix assisted laser desorption ionization (MALDI) MS are effective for underglycosylation analyses of intact serum Transferrin (Tf) in CDG-I patients by mass determination of individual component glycoforms.
Expression and function of iron-regulatory proteins in retina.
Ganapathy et al., Augusta, United States. In Iubmb Life, 2010
Hemochromatosis, a genetic disorder of iron overload, is caused by mutations in at least five genes, namely HFE, hemojuvelin, Transferrin receptor 2, ferroportin, and hepcidin.
Hemochromatosis and Vibrio vulnificus wound infections.
Acton et al., Birmingham, United States. In J Clin Gastroenterol, 2009
Transferrin saturation was 89% and serum ferritin was 4761 pmol/L.
[CDT: a biological marker of alcohol abuse].
Ferrario et al., Varese, Italy. In Med Lav, 2007
CONCLUSIONS: CDT (Carbohydrate-Deficient-Transferrin) meets all these requirements and offers the physician a significant tool as a marker of chronic alcohol abuse.
REKLYS et al., In Science, 1965
Eleven molecular forms and 34 phenotypes of transferrin have been detected in 372 serums from six macaque species.
ARENDS et al., In Science, 1964
Three different phenotypes were found and denominated A, B, and C. Four serums could not be classified because their transferrin apparently did not bind iron-59, possibly owing to saturation.
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