transcription factor IIB
In vitro fluorescence studies of transcription factor IIB-DNA interaction.
Kraków, Poland. In Acta Biochim Pol, 2014
General transcription factor TFIIB is one of the basal constituents of the preinitiation complex of eukaryotic RNA polymerase II, acting as a bridge between the preinitiation complex and the polymerase, and binding promoter DNA in an asymmetric manner, thereby defining the direction of the transcription.
A nano-positioning system for macromolecular structural analysis.
München, Germany. In Nat Methods, 2008
We applied this method to find the position of the 5' end of the nascent RNA exiting transcription elongation complexes of yeast (Saccharomyces cerevisiae) RNA polymerase II and studied the influence of transcription factor IIB on the position of the RNA.
Trajectory of DNA in the RNA polymerase II transcription preinitiation complex.
United States. In Proc Natl Acad Sci U S A, 1997
By using site-specific protein-DNA photocrosslinking, we define the positions of TATA-binding protein, transcription factor IIB, transcription factor IIF, and subunits of RNA polymerase II (RNAPII) relative to promoter DNA within the human transcription preinitiation complex.
X-ray crystallographic studies of eukaryotic transcription initiation factors.
New York City, United States. In Philos Trans R Soc Lond B Biol Sci, 1996
Substantial progress has also been made on structural and mechanistic studies, including our three-dimensional crystal structures of TBP, TBP bound to a consensus TATA elements, and the ternary complex of transcription factor IIB (TFIIB) recognizing TBP bound to a TATA element.
The TATA box binding protein.
New York City, United States. In Curr Opin Struct Biol, 1996
Three-dimensional structures newly elucidated include two TATA box binding proteins alone and bound to distinct TATA elements, and the ternary complex of transcription factor IIB recognizing a TATA box binding protein bound to a TATA element.