The Latent Membrane Protein 1 (LMP1).
München, Germany. In Curr Top Microbiol Immunol, 2014
By acting like a constitutively active receptor, LMP1 recruits cellular signaling molecules associated with tumor necrosis factor receptors such as tumor necrosis factor receptor-associated factor (TRAF) proteins and TRADD to mimic signals of the costimulatory CD40 receptor in the EBV-infected B lymphocyte.
Review: ototoxic characteristics of platinum antitumor drugs.
Buffalo, United States. In Anat Rec (hoboken), 2012
Combined treatment with ethacrynic acid (a loop diuretic) and cisplatin results in rapid apoptotic hair cell death characterized by upregulation of initiator caspase-8 and membrane death receptor, TRADD, followed by downstream executioners, caspase-3 and caspase-6.
The role of TRADD in death receptor signaling.
Bethesda, United States. In Cell Cycle, 2012
TRADD (TNFR1-associated death domain protein) was initially identified as an adaptor molecule that transduces the signal downstream of the TNFR1 (tumor necrosis factor receptor 1).