Apolipoprotein E and familial longevity.
New York City, United States. In Neurobiol Aging, 30 Apr 2013
The ε4 allele in apolipoprotein E and the linked G allele in rs2075650 of TOMM40 have been associated with increased mortality and the ε2 allele with decreased mortality, although inconsistently.
[Risk factors for Alzheimer's disease].
Kanazawa, Japan. In Brain Nerve, 2010
In addition, several genes such as CTNNA3, GAB2, PVRL2, TOMM40, and APOC1 are known to be the risk factors that contribute to AD pathogenesis.
An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease.
Durham, United States. In Arch Neurol, 2010
I coauthored a recently published research article describing a variable length, poly-T polymorphism in the TOMM40 gene, adjacent to apolipoprotein E (APOE) on chromosome 19, that accounts for the age at onset distribution for a complex disease, late-onset Alzheimer disease.
Protein import into mitochondria of Neurospora crassa.
München, Germany. In Fungal Genet Biol, 2002
The translocase of the mitochondrial outer membrane, the TOM complex, comprises receptors which specifically recognize mitochondrial preproteins and a protein conducting channel formed by TOM40.
Mitochondrial protein import.
Marseille, France. In J Bioenerg Biomembr, 1990
In yeast, a 42-kilodalton protein (ISP42) probably forms part of the outer membrane channel.