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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Target of myb1-like 1

Tom1L1, Srcasm
Top mentioned proteins: Src, TOM1, Tom1L2, Stam, HRs
Papers on Tom1L1
Novel genes and hormonal regulation for gonadal development during embryogenesis in chickens.
New
Song et al., Seoul, South Korea. In Gen Comp Endocrinol, Feb 2015
Therefore, we focused on three genes (TOM1L1, TTR, and ZEB1) that are related to cellular proliferation and embryonic development based on previous study indicating up- or down-regulated transcripts in the asymmetric female gonads between embryonic day 6 (E6) and E9 by microarray analyses.
Identification of novel regulatory genes in development of the avian reproductive tracts.
Song et al., Seoul, South Korea. In Plos One, 2013
Therefore, in the present study, we investigated the expression patterns of four genes including SNCA, TOM1L1, TTR and ZEB1 in the gonads at embryonic days 14 and 18, and in immature (12-week-old) and mature (50-week-old) chickens, as well as the reproductive tract including ovary, oviduct and testes of the respective sexes by qRT-PCR, in situ hybridization and immunofluorescence analyses.
Analysis of SRC oncogenic signaling in colorectal cancer by stable isotope labeling with heavy amino acids in mouse xenografts.
Roche et al., Montpellier, France. In Mol Cell Proteomics, 2012
We next confirmed this notion experimentally with the example of the vesicular trafficking protein and SRC substrate TOM1L1.
Multivesicular bodies in the enigmatic amoeboflagellate Breviata anathema and the evolution of ESCRT 0.
Dacks et al., Edmonton, Canada. In J Cell Sci, 2011
We determine the distribution of Tom1 family proteins across eukaryotes and show that the Tom1, Tom1L1 and Tom1L2 proteins are a vertebrate-specific expansion of the single Tom1 family ancestor, which has indeed been identified in at least one member of each of the major eukaryotic supergroups.
Epigenetic predictor of age.
Vilain et al., Los Angeles, United States. In Plos One, 2010
The methylation of three sites--in the promoters of the EDARADD, TOM1L1, and NPTX2 genes--is linear with age over a range of five decades.
The emerging role of VHS domain-containing Tom1, Tom1L1 and Tom1L2 in membrane trafficking.
Review
Hong et al., Xiamen, China. In Traffic, 2010
Recent studies suggest that Tom1, Tom1L1 and Tom1L2 subfamily of VHS domain proteins, which do not exist in yeast, are emerging as novel regulators for post-Golgi trafficking and signaling.
Decreased Srcasm expression in esophageal squamous cell carcinoma in a Chinese population.
GeneRIF
Seykora et al., Zhengzhou, China. In Anticancer Res, 2010
This pattern of Srcasm expression suggests that it may act as a negative regulator in esophageal squamous cell carcinoma cell signaling
Srcasm inhibits Fyn-induced cutaneous carcinogenesis with modulation of Notch1 and p53.
Seykora et al., Philadelphia, United States. In Cancer Res, 2010
Increasing Srcasm levels using a K14-Fyn Y528F/K14-Srcasm double transgenic model markedly inhibited cutaneous neoplasia.
Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor.
GeneRIF
Hong et al., Singapore, Singapore. In Embo J, 2009
Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor.
Decreased Srcasm expression in hyperproliferative cutaneous lesions.
GeneRIF
Seykora et al., Philadelphia, United States. In J Cutan Pathol, 2009
All multicentric and nodular basal cell carcinomas displayed a prominent loss of Srcasm staining in association with a marked increase in Ki-67 staining.
TOM1L is involved in a novel signaling pathway important for the IL-2 production in Jurkat T cells stimulated by CD3/CD28 co-ligation.
GeneRIF
Kjellen et al., Örebro, Sweden. In Mediators Inflamm, 2008
results imply that TOM1L has a mitogenic effect in Jurkat T-cells and is involved in a novel cell signaling pathway that is crucial for the IL-2 production and STAT3 expression
Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.
Dusetti et al., Marseille, France. In Proteomics, 2008
Among them we have found several molecules that modulate cell proliferation and survival (CIZ1, BIRC6, RBBP6), signaling (LTBP4, Notch2, TOM1L1, STK24) and membrane dynamics (PLSCR1, DDEF2, VCP).
Tom1l2 hypomorphic mice exhibit increased incidence of infections and tumors and abnormal immunologic response.
Elsea et al., Richmond, United States. In Mamm Genome, 2008
Studies have shown that the TOM1 family of proteins, including TOM1 and TOM1L1, are actively involved in endosomal trafficking and function in the immune response.
TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells.
Siraganian et al., Bethesda, United States. In J Biol Chem, 2008
A potential substrate of Lyn identified was the molecule TOM1L1, which has several domains thought to be important for membrane trafficking and protein-protein interactions.
Recruitment of Tom1L1/Srcasm to endosomes and the midbody by Tsg101.
GeneRIF
Nakayama et al., Kyoto, Japan. In Cell Struct Funct, 2007
study found that not only the PTAP sequence in the GAT domain but also the PSAP sequence in the C-terminal region of Tom1L1 is responsible for its interaction with the UEV domain of Tsg101 and competes with the HIV-1 Gag protein for the Tsg101 interaction
Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells.
Feller et al., Oxford, United Kingdom. In Cell Commun Signal, 2007
Mass spectrometric analyses of LckSH2-purified pY proteins subsequently identified several proteins readily known as SFK kinase substrates, including cortactin, Tom1L1 (SRCASM), GIT1, vimentin and AFAP1L2 (XB130).
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