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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Tumor necrosis factor, alpha-induced protein 8

TNF-induced protein, TNFAIP8, GG2-1, SCC-S2, NDED
Top mentioned proteins: HAD, CAN, POLYMERASE, NF-kappaB, PrP
Papers on TNF-induced protein
A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.
New
Cardozo et al., Brussels, Belgium. In Mol Endocrinol, Jan 2016
Genome-wide association studies have identified the gene TNF-induced protein 3 (TNFAIP3), encoding for the zinc finger protein A20, as a susceptibility locus for T1D.
Machine Learning-based Classification of Diffuse Large B-cell Lymphoma Patients by Their Protein Expression Profiles.
New
Mann et al., Martinsried, Germany. In Mol Cell Proteomics, Nov 2015
A panel of four proteins (PALD1, MME, TNFAIP8, and TBC1D4) is predicted to classify patients with low error rates.
TIPE2 Play a Negative Role in TLR4-Mediated Autoimmune T Helper 17 Cell Responses in Patients with Myasthenia Gravis.
New
Liu et al., Xuzhou, China. In J Neuroimmune Pharmacol, Nov 2015
UNASSIGNED: Th17-related cytokines have been suggested to play a crucial role in myasthenia gravis (MG) pathogenesis.The tumor necrosis factor (TNF)-α-induced protein 8-like-2 (TNFAIP8L2 or TIPE2), is a newly identified member of the tumor necrosis TNFAIP8 family which is an essential negative regulator of both innate and adaptive immunity.
Tumour necrosis factor-alpha-induced protein 8 (TNFAIP8) expression associated with cell survival and death in cancer cell lines infected with canine distemper virus.
New
Cardoso et al., Araçatuba, Brazil. In Vet Comp Oncol, Oct 2015
In this study, three human mammary tumour cell lines and one canine-derived adenofibrosarcoma cell line were tested regarding to their susceptibility to CDV infection, cell proliferation, apoptosis, mitochondrial membrane potential and expression of tumour necrosis factor-alpha-induced protein 8 (TNFAIP8).
Expression of tumor necrosis factor α-induced protein 8 is upregulated in human gastric cancer and regulates cell proliferation, invasion and migration.
New
Guo et al., Jinan, China. In Mol Med Report, Aug 2015
Tumor necrosis factor α-induced protein 8 (TNFAIP8) has been associated with the tumorigenicity of various types of cancer, however, the expression of TNFAIP8 and its function in gastric cancer remain to be fully elucidated.
Exacerbated experimental colitis in TNFAIP8-deficient mice.
New
Chen et al., China. In J Immunol, Jul 2015
The TNF-α-induced protein 8 (TNFAIP8 or TIPE) is a risk factor for cancer and bacterial infection, and its expression is upregulated in a number of human cancers.
Crucial roles of TNFAIP8 protein in regulating apoptosis and Listeria infection.
New
Chen et al., China. In J Immunol, Jul 2015
TNF-α-induced protein 8 (TNFAIP8 or TIPE) is a newly described regulator of cancer and infection.
Genome-wide analysis of androgen receptor binding sites in prostate cancer cells.
New
Tao et al., Hangzhou, China. In Exp Ther Med, Jun 2015
The major genes in the different GO terms were TNFAIP8, RTN4, APP and SYNE1.
Identical expression profiling of human and murine TIPE3 protein reveals links to its functions.
New
Liu et al., China. In J Histochem Cytochem, Mar 2015
Tumor necrosis factor-alpha-induced protein-8 like-3 (TNFAIP8L3, TIPE3) is a newly discovered member of TNFAIP8 family and regarded as a lipid second messenger transfer protein that promotes cancer.
The Drosophila TIPE family member Sigmar interacts with the Ste20-like kinase Misshapen and modulates JNK signaling, cytoskeletal remodeling and autophagy.
Gorski et al., Vancouver, Canada. In Biol Open, 2014
TNFAIP8 and other mammalian TIPE family proteins have attracted increased interest due to their associations with disease-related processes including oncogenic transformation, metastasis, and inflammation.
In Silico Analysis of Tumor Necrosis Factor α-Induced Protein 8-Like-1 (TIPE1) Protein.
Xu et al., Zhenjiang, China. In Plos One, 2014
Tumor necrosis factor α-induced protein 8 (TNFAIP8)-like protein 1 (TIPE1) was a member of TNFAIP8 family.
Levels of selected oxidative stress markers in the vitreous and serum of diabetic retinopathy patients.
Đikić et al., Zagreb, Croatia. In Mol Vis, 2014
METHODS: The study included and compared two groups of patients who underwent vitrectomy: 37 patients with type 2 diabetes and proliferative retinopathy (PDR), and 50 patients with non-diabetic eye disorders (NDED).
Tumor necrosis factor-α induced protein 8 polymorphism and risk of non-Hodgkin's lymphoma in a Chinese population: a case-control study.
GeneRIF
Zhou et al., Shanghai, China. In Plos One, 2011
polymorphism of TNFAIP8 rs1045241C>T may contribute to NHL susceptibility in a Chinese population
The TIPE (TNFAIP8) family in inflammation, immunity, and cancer.
Review
Liu et al., China. In Mol Immunol, 2011
Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8 or TIPE) family are recently identified proteins which are important for maintaining immune homeostasis.
TNFAIP8: a new effector for Galpha(i) coupling to reduce cell death and induce cell transformation.
GeneRIF
Albert et al., Ottawa, Canada. In J Cell Physiol, 2010
Data suggest that Galphai-TNFAIP8-mediated rescue of pre-oncogenic cells enhances progression to oncogenic transformation, providing a selective target to inhibit cellular transformation.
Expression and regulation of a novel identified TNFAIP8 family is associated with diabetic nephropathy.
GeneRIF
Yi et al., Jinan, China. In Biochim Biophys Acta, 2010
Findings demonstrate that TNFAIP8 is one of critical components of a signal transduction pathway that links mesangial cell proliferation to diabetic renal injury.
Overexpression of SCC-S2 correlates with lymph node metastasis and poor prognosis in patients with non-small-cell lung cancer.
GeneRIF
Wang et al., Shenyang, China. In Cancer Sci, 2010
SCC-S2 plays an important role in NSCLC and might be a useful therapeutic target of NSCLC.
Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses.
GeneRIF
Fowler et al., Durham, United States. In Plos Pathog, 2009
Tnfaip8 expression is associated with susceptibility to Staphylococcus aureus sepsis.
TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis.
Impact
Chen et al., Philadelphia, United States. In Cell, 2008
We report here the identification of a member of the tumor necrosis factor-alpha-induced protein-8 (TNFAIP8) family, designated TIPE2, that is required for maintaining immune homeostasis.
"Promoter array" studies identify cohorts of genes directly regulated by methylation, copy number change, or transcription factor binding in human cancer cells.
Review
Mercola et al., San Diego, United States. In Ann N Y Acad Sci, 2005
The vast majority of genes that appear to be both differentially methylated and differentially regulated between prostate epithelial and cancer cell lines are novel methylation targets, including PAK6, RAD50, TLX3, PIR51, MAP2K5, INSR, FBN1, GG2-1, representing a rich new source of candidate genes to study the role of DNA methylation in prostate tumors.
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