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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Transmembrane protein 135

Top mentioned proteins: SET, GATA4, DKK1, Wnt16, mTOR
Papers on TMEM135
Intelligence: shared genetic basis between Mendelian disorders and a polygenic trait.
Boomsma et al., Amsterdam, Netherlands. In Eur J Hum Genet, Oct 2015
Using both single-nucleotide polymorphism (SNP)- and gene-based association testing, we detected an association between intelligence and the genes of interest, with genes ELP2, TMEM135, PRMT10, and RGS7 showing the strongest associations.
Novel fusion transcripts associate with progressive prostate cancer.
Luo et al., In Am J Pathol, 2014
The analyses indicated that most patients [69 (91%) of 76] positive for any of these fusion transcripts (TRMT11-GRIK2, SLC45A2-AMACR, MTOR-TP53BP1, LRRC59-FLJ60017, TMEM135-CCDC67, KDM4-AC011523.2, MAN2A1-FER, and CCNH-C5orf30) experienced PCa recurrence, metastases, and/or PCa-specific death after radical prostatectomy.
Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium.
Kaptoge et al., Cambridge, United Kingdom. In Hum Mol Genet, 2014
(rs597319 close to TMEM135, a gene recently linked to osteoblastogenesis and longevity) significantly associated with both BUA and VOS (P < 8.23 × 10(-14)).
A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers.
Reis-Filho et al., London, United Kingdom. In J Pathol, 2012
Sequencing analysis of independent cohorts of hereditary BRCA1 and sporadic non-BRCA1 breast cancers for the presence of recurrent pathogenic mutations and/or homozygous deletions found in the index cases revealed that DAPK3, TMEM135, KIAA1797, PDE4D, and GATA4 are potential additional drivers of breast cancers.
Single nucleotide polymorphisms associated with risk for contralateral breast cancer in the Women's Environment, Cancer, and Radiation Epidemiology (WECARE) Study.
Concannon et al., Charlottesville, United States. In Breast Cancer Res, 2010
and rs11235127 near TMEM135 (per allele RR = 1.26, 95%CI = 1.04-1.53).
Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and longevity regulation in Caenorhabditis elegans.
Aschner et al., Nashville, United States. In Plos One, 2009
The present study uses a dual approach employing both C57BL/6 mice and the nematode, C. elegans, to focus on TMEM135, a conserved protein which we have found to be upregulated 4.3 (±0.14)-fold in VLCAD-deficient mice at birth.
Comparative transcriptomics of human multipotent stem cells during adipogenesis and osteoblastogenesis.
Trajanoski et al., Graz, Austria. In Bmc Genomics, 2007
Four of these genes were studied in more detail: LXRalpha and phospholipid transfer protein (PLTP) for adipogenesis, the nuclear receptor COUP-TF1 and one uncharacterized gene, TMEM135 for osteoblastogenesis.
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