Congenital fiber type disproportion myopathy caused by LMNA mutations.
Tokyo, Japan. In J Neurol Sci, 05 Apr 2014
Importantly, all FTD associated with LMNA-myopathy were caused by hypertrophy of type 2 fibers as compared with age-matched controls, whereas CFTD with mutations in ACTA1 or TPM3 showed selective type 1 fiber atrophy but no type 2 fiber hypertrophy.
Differential stability of the crystallographic interfaces of mu- and kappa-opioid receptors.
New York City, United States. In Plos One, Dec 2013
The recent mu-opioid receptor (MOPr) and kappa-opioid receptor (KOPr) crystal structures have inspired hypotheses of physiologically relevant dimerization contacts, specifically: a closely packed interface involving transmembrane (TM) helices TM5 and TM6, and a less compact interface, involving TM1, TM2, and helix 8 (H8).