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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.


TIA, T1a, TIA-1
This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, AGE, CAN, iMpact, CD8
Papers using TIA antibodies
Cytotoxic T-cell non-Hodgkin's lymphoma of the thyroid gland
Lee Young-Don et al., In Journal of Korean Medical Science, 2004
... Glostrup, Denmark, prediluted), CD20 (Dako, prediluted), CD4 (Dako, prediluted), CD8 (Dako, prediluted), T-cell-restricted intracellular antigen-1 (TIA-1, Dako, prediluted), granzyme B (Dako, prediluted), ...
Dynamic relocation of transcription and splicing factors dependent upon transcriptional activity
Anderson Paul et al., In The Journal of Cell Biology, 1996
... Goat anti–TIA-1 polyclonal antibody was obtained from Santa Cruz Biotechnology, Inc., and anti-hemagglutinin (HA) ...
Papers on TIA
Laparoscopic Radiofrequency Ablation versus Partial Nephrectomy for cT1a Renal Tumors: Long-Term Outcome of 179 Patients.
Guo et al., Nanjing, China. In Urol Int, Feb 2016
OBJECTIVES: To compare the long-term functional and oncological results between laparoscopic radiofrequency ablation (LRFA) and laparoscopic partial nephrectomy (LPN) in selected clinical T1a (cT1a) renal tumor patients.
Sirt1 positive lymphocytes in acute cellular cardiac allograft rejection: contributor to pathogenesis and a therapeutic target.
Brown et al., Houston, United States. In Asaio J, Feb 2016
CD3, CD4, CD8, CD20, CD68, TIA-1, and Sirt1 expression were determined by immunohistochemical (IHC) stains.
Prospective Phase II Trial of Once-weekly Hypofractionated Radiation Therapy for Low-risk Adenocarcinoma of the Prostate: Late Toxicities and Outcomes.
Lambert et al., Montréal, Canada. In Clin Oncol (r Coll Radiol), Feb 2016
MATERIALS AND METHODS: A multi-institutional phase II trial was conducted, using a three-dimensional conformal radiation therapy (3D-CRT) approach for low-risk prostate cancer (T1a-T2a, Gleason ≤ 6 and prostate-specific antigen ≤ 10 ng/ml).
Primary hepatic Epstein-Barr virus-associated CD30-positive peripheral T-cell lymphoma of cytotoxic phenotype.
Qing et al., Torrance, United States. In Exp Mol Pathol, Feb 2016
By immunohistochemistry, the lymphoma cells expressed CD2, CD3, CD8, CD30, CD43, CD45, granzyme B, TIA-1, and negative for CD4, CD5, CD7, CD56, βF1, ALK-1, and B-cell markers.
Magnitude of risk for nodal metastasis associated with lymphvascular space invasion for endometrial cancer.
Wright et al., Columbia, United States. In Gynecol Oncol, Feb 2016
METHODS: We identified patients with T1A (<50% myoinvasion) and T1B (>50% myoinvasion) endometrioid adenocarcinomas of the endometrium diagnosed between 2010 and 2012 and recorded in the National Cancer Database.
Endoscopic Management of Early Esophageal Cancer.
Willingham et al., Atlanta, United States. In J Clin Gastroenterol, Sep 2015
Although surgery remains the mainstay of treatment for more advanced tumors, national guidelines now recommend endoscopic mucosal resection followed by radiofrequency ablation for intramucosal carcinomas and T1a cancers.
Esophageal cancer: Risk factors, screening and endoscopic treatment in Western and Eastern countries.
Lanas Arbeloa et al., Zaragoza, Spain. In World J Gastroenterol, Aug 2015
The differences in the therapeutic management of early esophageal carcinoma (high-grade dysplasia, T1a, T1b, N0) between different parts of the world may be explained by the number of cancers diagnosed at an early stage.
Primary Esophageal Extranasal NK/T Cell Lymphoma With Biphasic Morphology: A Case Report and Literature Review.
Chen et al., Birmingham, United States. In Medicine (baltimore), Jul 2015
Immunohistochemical studies confirmed that both underlying atypical cells and superficial small lymphocytes were neoplastic, sharing an identical immunophenotype: positive for CD2, CD3, CD43, CD8, CD56, TIA-1 and granzyme B. Epstein-Barr virus-encoded small RNAs were found in both cells.
Concurrent Epstein-Barr virus associated NK/T cell lymphoma after immunosuppressive therapy for aplastic anemia: report of a case and review of literature.
Miao et al., Nanjing, China. In Int J Clin Exp Pathol, 2014
Increased heterotypic lymphocytes had been detected in the left side of parotid gland demonstrated as cCD3(+), CD56(+), GranB(+), TIA-1(+), MUM-1(+), KI-67 (50%-75%)(++), Bcl-6(-), MPO(-) by immunohistochemistry, and in-situ hybridization (ISH) indicated EBER positive.
Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in patients with stroke or transient ischaemic attack.
Wang et al., Beijing, China. In Cochrane Database Syst Rev, 2014
OBJECTIVES: To assess the efficacy and safety of PPAR-γ agonists in the secondary prevention of stroke and related vascular events for people with stroke or transient ischaemic attack (TIA).
Outcomes by tumor subtype and treatment pattern in women with small, node-negative breast cancer: a multi-institutional study.
Lin et al., Boston, United States. In J Clin Oncol, 2014
PURPOSE: Treatment decisions for patients with T1a,bN0M0 breast cancer are challenging.
Distant invasive breast cancer recurrence risk in human epidermal growth factor receptor 2-positive T1a and T1b node-negative localized breast cancer diagnosed from 2000 to 2006: a cohort from an integrated health care delivery system.
Habel et al., Loma Linda, United States. In J Clin Oncol, 2014
Among T1ab patients not treated with adjuvant trastuzumab or chemotherapy (n = 171), the 5-year invasive DRFI was 98.2% (95% CI, 94.5% to 99.4%); it was 99.0% (95% CI, 93.0% to 99.9%) for T1a patients, and 97.0% (95% CI, 88.6% to 99.2%) for T1b patients.
Evolutionary dynamics of gene and isoform regulation in Mammalian tissues.
Burge et al., Cambridge, United States. In Science, 2013
Thousands of previously unknown, lineage-specific, and conserved alternative exons were identified; widely conserved alternative exons had signatures of binding by MBNL, PTB, RBFOX, STAR, and TIA family splicing factors, implicating them as ancestral mammalian splicing regulators.
Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2.
Turley et al., Boston, United States. In Immunity, 2012
activation of CLEC-2 by PDPN rearranges the actin cytoskeleton in dendritic cells to promote efficient motility along stromal surfaces.
Expression of podoplanin in salivary gland adenoid cystic carcinoma and its association with distant metastasis and clinical outcomes.
Guo et al., Shanghai, China. In Mol Med Report, 2012
A close correlation is found between podoplanin expression and distant metastasis and disease-free survival.
Podoplanin lymphatic density and invasion correlate with adverse clinicopathologic and biological factors and survival in neuroblastomas.
May et al., Bristol, United Kingdom. In Am J Surg Pathol, 2012
Podoplanin has the potential to provide valuable prognostic information to clinic-ians for risk assessment of neuroblastomas.
Expression of podoplanin in nevoid basal cell carcinoma syndrome-associated keratocystic odontogenic tumours.
Zustin et al., Hamburg, Germany. In Anticancer Res, 2012
Podoplanin expression in Keratocystic odontogenic tumour (KCOT) is possibly associated with slow invasion of the adjacent structures and the well-known frequent local tumour recurrences of this odontogenic tumour.
Long-term survival following partial vs radical nephrectomy among older patients with early-stage kidney cancer.
Miller et al., Ann Arbor, United States. In Jama, 2012
DESIGN, SETTING, AND PATIENTS: We performed a retrospective cohort study of Medicare beneficiaries with clinical stage T1a kidney cancer treated with partial or radical nephrectomy from 1992 through 2007.
Platelet CLEC-2 and podoplanin in cancer metastasis.
Watson et al., Birmingham, United Kingdom. In Thromb Res, 2012
Here, the bidirectional relationship between CLEC-2 and podoplanin is described and considered in the context of tumour growth and metastasis.
Apixaban versus aspirin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a predefined subgroup analysis from AVERROES, a randomised trial.
AVERROES Steering Committee and Investigators et al., Essen, Germany. In Lancet Neurol, 2012
We aimed to investigate whether the subgroup of patients with previous stroke or transient ischaemic attack (TIA) would show a greater benefit from apixaban compared with aspirin than would patients without previous cerebrovascular events.
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