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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Thrombospondin, type I, domain containing 1

THSD1, thrombospondin type I domain-containing 1, Thrombospondin Type I Domain Containing
The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jan 2009] (from NCBI)
Top mentioned proteins: thrombospondin-1, Sip, Stathmin, TSG, Wip1
Papers on THSD1
Identification of embryonic lethal genes in humans by autozygosity mapping and exome sequencing in consanguineous families.
Alkuraya et al., Riyadh, Saudi Arabia. In Genome Biol, 2014
In addition to revealing mutations in genes previously linked to embryonic lethality in severe cases, our approach revealed seven novel candidate genes (THSD1, PIGC, UBN1, MYOM1, DNAH14, GALNT14, and FZD6).
Genome-wide screening for methylation-silenced genes in colorectal cancer.
Sugihara et al., Tokyo, Japan. In Int J Oncol, 2012
The THSD1 gene may play a role in the tumorigenesis of colorectal cancer
Thrombospondin type I domain containing 7A (THSD7A) mediates endothelial cell migration and tube formation.
Chuang et al., Taiwan. In J Cell Physiol, 2010
A novel endothelial protein, Thrombospondin Type I Domain Containing 7A (THSD7A), with preferential expression in placenta vasculature and in human umbilical vein endothelial cells (HUVECs) was identified and targeted for further characterization.
Monochromosome transfer and microarray analysis identify a critical tumor-suppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma.
Lung et al., Hong Kong, Hong Kong. In Mol Cancer Res, 2008
These findings suggest that THSD1 is a good candidate tumor suppressor gene.
Microarray analysis of radiation response genes in primary human fibroblasts.
Sáfrány et al., Budapest, Hungary. In Int J Radiat Oncol Biol Phys, 2007
Twenty of these consensus radiation response genes were functionally categorized: most of them belong to the DNA damage response (GADD45A, BTG2, PCNA, IER5), regulation of cell cycle and cell proliferation (CDKN1A, PPM1D, SERTAD1, PLK2, PLK3, CYR61), programmed cell death (BBC3, TP53INP1) and signaling (SH2D2A, SLIC1, GDF15, THSD1) pathways.
Immunolocalization of thrombospondin in the human and sand rat intervertebral disc.
Hanley et al., Charlotte, United States. In Spine (phila Pa 1976), 2006
The strong immunolocalization of thrombospondin (TSP) in the outer anulus of the intervertebral disc indicates a role for TSP in the avascular status of the adult human disc.
Thrombospondin induces RhoA inactivation through FAK-dependent signaling to stimulate focal adhesion disassembly.
Murphy-Ullrich et al., Birmingham, United States. In J Biol Chem, 2004
Thrombospondin has a role in inducing RhoA inactivation through FAK-dependent signaling to stimulate focal adhesion disassembly
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