Anticoagulant therapy for idiopathic pulmonary fibrosis
In Pulmonary Medicine, 2004
... Shino-test), the same antibody used for ELISA, RAGE (MAB5328, 1 : 50, CHEMICON International, Inc., Temecula, CA), thrombomodulin (TM1009, 1 : 100, DAKO Company Ltd., Glostrup, Denmark), ...
Pentraxin 3 as a biomarker of local inflammatory response to vascular injury in systemic lupus erythematosus.
Katowice, Poland. In Autoimmunity, 17 Dec 2014
All participants' plasma and serum samples were collected to estimate concentrations (ELISA) of PTX3, soluble thrombomodulin, soluble E-selectin (sE-selectin), soluble P-selectin (sP-selectin), soluble form of vascular cell adhesion molecule 1 (sVCAM-1), soluble inter-cellular adhesion molecule-1 (sICAM-1), soluble platelet endothelial cell adhesion molecule 1, monocyte chemotactic protein-1 (MCP-1) and von Willebrand factor (vWF) activity.
FGFR1 mediates recombinant thrombomodulin domain-induced angiogenesis.
Tainan City, Taiwan. In Cardiovasc Res, 10 Dec 2014
AIMS: The recombinant epidermal growth factor-like domain plus the serine/threonine-rich domain of thrombomodulin (rTMD23) promotes angiogenesis and accelerates the generation of activated protein C (APC), which facilitates angiogenesis.
Anticoagulant effects of statins and their clinical implications.
Kraków, Poland. In Thromb Haemost, Apr 2014
Anticoagulant properties of statins reported in experimental and clinical studies involve decreased tissue factor expression resulting in reduced thrombin generation and attenuation of pro-coagulant reactions catalysed by thrombin, such as fibrinogen cleavage, factor V and factor XIII activation, as well as enhanced endothelial thrombomodulin expression, resulting in increased protein C activation and factor Va inactivation.
Coagulopathy in malaria.
Bangkok, Thailand. In Thromb Res, Jan 2014
Elevated plasma levels of von Willebrand factor (vWF) and vWF propeptide, thrombomodulin, endothelial microparticles have been reported in P. falciparum-infected patients.
Traumatic coagulopathy--part 1: Pathophysiology and diagnosis.
Auburn, United States. In J Vet Emerg Crit Care (san Antonio), Jan 2014
Excessive activation of the thrombin-thrombomodulin activated Protein C pathway, catecholamine-induced endothelial damage as well as disseminated intravascular coagulation (DIC) with a fibrinolytic phenotype are all hypotheses that have been proposed in attempts to explain the functional mechanism of ATC.
New insights into modulation of thrombin formation.
Maastricht, Netherlands. In Curr Atheroscler Rep, Nov 2013
This protective effect is mediated in part through generation of anticoagulant enzymes, including activated protein C, formed on the action of thrombin on the endothelial receptor thrombomodulin.
[Morphological and molecular bases of cardiac development].
Laizhou, China. In Postepy Hig Med Dosw (online), 2012
Their expression is regulated by various molecules, including transcription (XIN, GATA, MEF, Tbx5, Baf60c, PECAM, tie-2, MEF2) and growth (VEGF, FGF, PDGF) factors, as well as proteins (i.e., dickkopf-1, cerberus, cytotactin, fibrillin, nodal, thrombomodulin, Wnt, bone morphometric ones - BMP2, BMP 4, BMP5, BMP7) and other substances, such as retinoid and folic acid.