A case of thyroid hormone resistance: a rare mutation.
Lisbon, Portugal. In Arq Bras Endocrinol Metabol, Dec 2014
Peripheral blood DNA was extracted from the patient and a mutation was found localized in cluster one, at codon 346 of the ligand binding domain of the THRB gene.
Rare thyroid non-neoplastic diseases.
Poznań, Poland. In Thyroid Res, Dec 2014
Thyroid hormone resistance is most commonly found in THRB gene mutations and more rarely in THRA mutations; in some cases both genes are unchanged (non-TR RTH).
Resistance to thyroid hormone.
Izumo, Japan. In Endocr Dev, 2013
RTHβ (formerly only RTH) is caused by mutations in the thyroid hormone receptor β gene (THRB).
Connecting cis-elements and trans-factors with mechanisms of developmental regulation of mRNA translation in meiotic and haploid mammalian spermatogenic cells.
Boston, United States. In Reproduction, 2013
As a result, the mechanisms involving well-studied mRNAs (Ddx4/Mvh, Prm1, Prm2, and Sycp3) and factors (DICER1, CPEB1, DAZL, DDX4/MVH, DDX25/GRTH, translin, and ELAV1/HuR) are incompletely understood.