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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

THO complex 1

THO1, CC3, TIP30, HCC-1
HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).[supplied by OMIM, Nov 2010] (from NCBI)
Top mentioned proteins: CAN, PrP, TSG101, HAD, OUT
Papers on THO1
Multiple calibrator measurements improve accuracy and stability estimates of automated assays.
Klee et al., Rochester, United States. In Scand J Clin Lab Invest, Feb 2016
Methods Three calibration procedures (CC1, CC2 and CC3) combined 12, 34 and 56 calibrator measurements over 1, 2, and 3 days.
A chiral porous organic cage for molecular recognition using gas chromatography.
Yuan et al., Kunming, China. In Anal Chim Acta, Feb 2016
By comparing the chiral recognition ability of the CC9-coated column with the commercially available β-DEX 120 column and the POC CC3-R coated column recently reported by our group, the CC9-coated column offered good resolution during the separation of some racemates, that were not separated using the β-DEX 120 column or POC CC3-R coated column.
Porous organic cages for sulfur hexafluoride separation.
Cooper et al., In J Am Chem Soc, Feb 2016
Despite lacking any metal sites, a porous cage, CC3, shows the highest SF6/N2 selectivity reported for any material at ambient temperature and pressure, which translates to real separations in a gas breakthrough column.
Metformin inhibits the pro-metastatic effect of Sorafenib in hepatocellular carcinoma by upregulating the expression of TIP30.
Zhang et al., Tianjin, China. In Cancer Sci, Feb 2016
UNASSIGNED: We previously found that a low dose of Sorafenib had a pro-metastatic effect on hepatocellular carcinoma (HCC), which was caused by down-regulation of TIP30 expression.
Overexpression of TIP30 inhibits the growth and invasion of glioma cells.
Luo et al., Guangzhou, China. In Mol Med Report, Jan 2016
TIP30 is a tumor suppressor involved in the regulation of numerous cellular processes, including tumor cell growth, metastasis, and angiogenesis in various human cancers.
Highly selective separation of enantiomers using a chiral porous organic cage.
Yuan et al., Shanghai, China. In J Chromatogr A, Jan 2016
The fabricated column complements to commercial β-DEX 120 column and our recently reported CC3-R column for separating enantiomers, which indicates that the excellent chiral recognition ability of CC10 is not only interesting academically, but also has potential for practical application.
Morphokinetics of embryos developed from oocytes matured in vitro.
Fadini et al., Monza, Italy. In J Assist Reprod Genet, Jan 2016
The morphokinetics of embryos selected for transfer or cryopreservation, derived from EC-MII and CC oocytes, were comparatively and retrospectively analyzed in terms of cleavage times (t2, t3, t4, t5, and t8) and intervals (cc2, cc3, s2, s3).
Effects of Lipopolysaccharide and Progesterone Exposures on Embryonic Cerebral Cortex Development in Mice.
Hevner et al., Seattle, United States. In Reprod Sci, Dec 2015
Two-color immunofluorescence was performed with primary antibodies T-box transcription factor 2 (Tbr2), ionized calcium binding adapter molecule 1 (Iba1), cleaved caspase 3 (CC3), and 5-bromo-2'-deoxyuridine (BrdU).
Complete versus incomplete cytoreduction in peritoneal carcinosis from gastric cancer, with consideration to PCI cut-off. Systematic review and meta-analysis.
Ansaloni et al., Bergamo, Italy. In Eur J Surg Oncol, Jul 2015
RESULTS: Nine trials have been included (748 patients: 417 with CC0-CC1 and 324 with CC2-CC3 cytoreduction).
TIP30: A Novel Tumor-Suppressor Gene.
Wu et al., Beijing, China. In Oncol Res, 2014
TIP30/CC3 was first identified and characterized as a "candidate" tumor-suppressor gene in 1997.
ITSN2L Interacts with and Negatively Regulates RABEP1.
Xiang et al., Changsha, China. In Int J Mol Sci, 2014
In this study, RABEP1 was identified as a novel ITSN2L interacting protein using a yeast two-hybrid screen from a human brain cDNA library and this interaction, specifically involving the ITSN2L CC domain and RABEP1 CC3 regions, was further confirmed by in vitro GST (glutathione-S-transferase) pull-down and in vivo co-immunoprecipitation assays.
GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4.
Stephens et al., Cambridge, United Kingdom. In Embo J, 2012
GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4.
Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.
McColl et al., Adelaide, Australia. In Oncogene, 2012
knockdown of p84 in MDA-MB-231 cells enhanced Akt phosphorylation and lung colonization
CAPER-α alternative splicing regulates the expression of vascular endothelial growth factor₁₆₅ in Ewing sarcoma cells.
Kleinerman et al., Houston, United States. In Cancer, 2012
Increased VEGF(165) expression is secondary to the down-regulation of CAPER-alpha by EWS/FLI-1. CAPER-alpha mediates alternative splicing and controls the shift from VEGF(189) to VEGF(165) .
Genome instability and transcription elongation impairment in human cells depleted of THO/TREX.
Aguilera et al., Sevilla, Spain. In Plos Genet, 2011
We show that human THO depletion impairs transcription elongation and mRNA export and increases instability associated with DNA breaks, leading to hyper-recombination and gammaH2AX and 53BP1 foci accumulation
Genetic enhancement of behavioral itch responses in mice lacking phosphoinositide 3-kinase-γ (PI3Kγ).
Zhuo et al., Seoul, South Korea. In Mol Pain, 2010
that genetic deletion of PI3Kgamma enhanced scratching behaviours in histamine-dependent and protease-activated receptor 2 (PAR-2)-dependent itch.
Factors that retard remyelination in multiple sclerosis with a focus on TIP30: a novel therapeutic target.
Suzuki et al., Tokyo, Japan. In Expert Opin Ther Targets, 2009
we examine the pathophysiological nature of remyelination failure in chronic multiple sclerosis and discuss the role of TIP30 as a novel therapeutic target--review
Cell death and autophagy: cytokines, drugs, and nutritional factors.
Gerner et al., Vienna, Austria. In Toxicology, 2009
For instance, using a newly established hepatoma cell line HCC-1.2,
Perioperative guidelines for elective surgery in the human immunodeficiency virus-positive patient.
Hutchison et al., Washington, D.C., United States. In Plast Reconstr Surg, 2008
RESULTS: Specific risk factors influencing operative morbidity include an absolute CD4 count of less than 200 cells/cc3 or viral load greater than 10,000 copies/ml.
Agents against cytokine synthesis or receptors.
Ichinose et al., Wakayama, Japan. In Eur J Pharmacol, 2006
Chemokine CC3 receptor antagonists, which block eosinophil chemotaxis, are now in clinical development for asthma therapy.
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