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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

TGFA transforming growth factor, alpha

TGFA
Top mentioned proteins: LIP, EGFR, Epidermal Growth Factor, HAD, CAN
Papers on TGFA
Association of Transforming Growth Factor Alpha Polymorphisms with Nonsyndromic Cleft Lip and Palate in Iranian Population.
New
Ameli et al., Tehrān, Iran. In Avicenna J Med Biotechnol, Oct 2015
Transforming growth factor alpha (TGFA) is expressed at the medial edge epithelium of fusing palatal shelves during craniofacial development.
Generation of stomach tissue from mouse embryonic stem cells.
New
Impact
Kurisaki et al., Tsukuba, Japan. In Nat Cell Biol, Aug 2015
Furthermore, TGFA overexpression in e-ST caused hypertrophic mucus and gastric anacidity, which mimicked Ménétrier disease in vitro.
Influence of Cancer-Associated Endometrial Stromal Cells on Hormone-Driven Endometrial Tumor Growth.
New
Kim et al., Chicago, United States. In Horm Cancer, Aug 2015
Using an angiogenesis focused real-time array TGFA, TGFB2 and TGFBR1 and VEGFC were identified as potential candidates for hormone-influenced growth regulation of tumors in the presence of benign and high-grade stromal cells.
Gene expression markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance).
New
Nixon et al., Durham, United States. In Clin Cancer Res, Apr 2015
qRT-PCR analyses were conducted on tissues from 103 patients at baseline to measure gene expression levels of HER-related genes, including amphiregulin (AREG), betacellulin (BTC), NT5E (CD73), DUSP4, EGF, EGFR, epigen (EPGN), epiregulin (EREG), HBEGF, ERBB2 (HER2), ERBB3 (HER3), ERBB4 (HER4), PHLDA1, and TGFA.
Reduced expression of the epidermal growth factor signaling system in preeclampsia.
New
Leach et al., Detroit, United States. In Placenta, Mar 2015
EGF, transforming growth factor-α (TGFA), and heparin-binding EGF-like growth factor (HBEGF) were evaluated using ELISA in maternal plasma from another 20 pregnancies with or without preeclampsia.
GFA Taq I polymorphism and cleft lip with or without cleft palate (CL/P) risk.
Ma et al., Beijing, China. In Int J Clin Exp Med, 2014
The transforming growth factor alpha (TGFA) Taq I polymorphism has been indicated to be correlated with cleft lip with or without cleft palate (CL/P) susceptibility, but study results are still debatable.
Molecular patterns of subclinical and clinical rejection of kidney allograft: quantity matters.
Viklicky et al., Praha, Czech Republic. In Kidney Blood Press Res, 2014
RESULTS: Clinical inflammation group showed a increased expression of genes for chemotaxis mediating cytokines (CCL1, CCL17, CCL24, CCL25, CCL26), cytokine receptors (CCR1, CCRL2, IL1RAPL2, CXCR5), proinflammatory cytokines (IL12A, LTA), inflammatory mediator (PTAFR), complement protein C3, executioner protein of apoptosis (CASP7), growth factor (TGFA), colony stimulating factor (CSF-2), proteins involved in dendritic cells differentiation and interaction (CD209, LAMP3), regulation of immune response (LILRB2, LILBRB4).
Whole-genome cartography of p53 response elements ranked on transactivation potential.
Inga et al., Trento, Italy. In Bmc Genomics, 2014
Based on the mapping of predicted functional REs near TSS, we examined expression changes of thirteen genes as a function of different p53-inducing conditions, providing further evidence for PDE2A, GAS6, E2F7, APOBEC3H, KCTD1, TRIM32, DICER, HRAS, KITLG and TGFA p53-dependent regulation, while MAP2K3, DNAJA1 and potentially YAP1 were identified as new direct p53 target genes.
Kcnj10 is a major type of K+ channel in mouse corneal epithelial cells and plays a role in initiating EGFR signaling.
Lin et al., Valhalla, United States. In Am J Physiol Cell Physiol, 2014
We used primary mouse corneal epithelial cells (pMCE) to examine the role of Kcnj10 in determining membrane K(+) conductance and cell membrane potential and in regulating EGF/TGFA release.
From wavy hair to naked proteins: the role of transforming growth factor alpha in health and disease.
Review
Coffey et al., Nashville, United States. In Semin Cell Dev Biol, 2014
Since its discovery in 1978 and cloning in 1984, transforming growth factor-alpha (TGF-α, TGFA) has been one of the most extensively studied EGF receptor (EGFR) ligands.
Contribution of transforming growth factor α polymorphisms to nonsyndromic orofacial clefts: a HuGE review and meta-analysis.
Review
Li et al., In Am J Epidemiol, 2014
We performed a meta-analysis of the association of transforming growth factor α gene (TGFA) polymorphisms with the risk of cleft lip with or without cleft palate (CL/P) or cleft palate (CP).
Dental agenesis: genetic and clinical perspectives.
Review
Huysseune et al., Gent, Belgium. In J Oral Pathol Med, 2009
At present, the list of genes involved in human non-syndromic hypodontia includes not only those encoding a signaling molecule (TGFA) and transcription factors (MSX1 and PAX9) that play critical roles during early craniofacial development, but also genes coding for a protein involved in canonical Wnt signaling (AXIN2), and a transmembrane receptor of fibroblast growth factors (FGFR1).
Meta-analysis and meta-review of thyroid cancer gene expression profiling studies identifies important diagnostic biomarkers.
Review
Impact
Wiseman et al., Vancouver, Canada. In J Clin Oncol, 2006
A review of the top 12 candidates revealed well known thyroid cancer markers such as MET, TFF3, SERPINA1, TIMP1, FN1, and TPO as well as relatively novel or uncharacterized genes such as TGFA, QPCT, CRABP1, FCGBP, EPS8 and PROS1.
Association between the transforming growth factor alpha gene and nonsyndromic oral clefts: a HuGE review.
Review
Vieira, Pittsburgh, United States. In Am J Epidemiol, 2006
Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor.
Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure.
Impact
Werb et al., San Francisco, United States. In Nat Genet, 1999
Cleft lip and palate syndromes in humans are associated with polymorphisms in the gene (TGFA) encoding transforming growth factor-alpha (TGF-alpha), an epidermal growth factor receptor (EGFR) ligand made by most epithelia.
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