Etiology and early pathogenesis of malignant testicular germ cell tumors: towards possibilities for preinvasive diagnosis.
Rotterdam, Netherlands. In Asian J Androl, May 2015
Since 2009, several genome wide association studies (GWAS) have been published, reporting on single-nucleotide polymorphisms (SNPs) with significant associations in or near the genes KITLG, SPRY4, BAK1, DMRT1, TERT, ATF7IP, HPGDS, MAD1L1, RFWD3, TEX14, and PPM1E, likely to be related to TGCT development.
Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
Brisbane, Australia. In Nat Commun, 2013
We find 11 genome-wide-significant (P<5 × 10(-8)) loci, some including known iron-related genes (HFE, SLC40A1, TF, TFR2, TFRC, TMPRSS6) and others novel (ABO, ARNTL, FADS2, NAT2, TEX14).
Mouse germ cell clusters form by aggregation as well as clonal divisions.
Durham, United States. In Mech Dev, 2012
Several molecular components of intercellular bridges in mammalian cells have been identified, including TEX14, a protein required for the stabilization of intercellular bridges, and several associated proteins that are components of the cytokinesis complex.
Germ cell intercellular bridges.
Houston, United States. In Cold Spring Harb Perspect Biol, 2011
Mammalian germ cell intercellular bridges are composed of general cytokinesis components with additional germ cell-specific factors including TEX14.
Presumptive germ cells derived from mouse pluripotent somatic cell hybrids.
São Paulo, Brazil. In Differentiation, 2009
Presumptive GC obtained reacted positively with anti-EMA, Vasa, Fragilis and Dazl antibodies and expressed GC-specific genes, such as Vasa, Stella, Dazl, Piwil 2, Tex14, Bmp8b, Tdrd1 and Rnf17.