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TGFB-induced factor homeobox 2-like, X-linked 1

Tex1, TGIF homeobox
TEX1 is part of the TREX (transcription/export) complex, which includes THO2 (MIM 300395), HPR1 (MIM 606930), ALY (MIM 604171), and UAP56 (MIM 142560).[supplied by OMIM, Nov 2010] (from NCBI)
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Top mentioned proteins: TGIF, ACID, TRF1, POLYMERASE, LIM
Papers on Tex1
Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA.
Cheng et al., Shanghai, China. In Nucleic Acids Res, 2013
The mRNA export complex TREX (TREX) is known to contain Aly, UAP56, Tex1 and the THO complex, among which UAP56 is required for TREX assembly.
The yeast THO complex forms a 5-subunit assembly that directly interacts with active chromatin.
Valpuesta et al., Warsaw, Poland. In Bioarchitecture, 2012
Yeast THO has been described as a heterotetramer (Tho2, Hpr1, Mft1 and Thp2) that performs several functions through the interaction with other proteins like Tex1 or the mRNA export factors Sub2 and Yra1, with which it forms the TRanscription and EXport complex (TREX).
Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor.
Dziembowski et al., Madrid, Spain. In Embo J, 2012
In yeast, this complex has been described as a heterotetramer (Tho2, Hpr1, Mft1, and Thp2) that interacts with Tex1 and mRNA export factors Sub2 and Yra1 to form the TRanscription EXport (TREX) complex.
Cell biological characterization of the malaria vaccine candidate trophozoite exported protein 1.
Felger et al., Basel, Switzerland. In Plos One, 2011
This protein is exported in the trophozoite stage and was named accordingly Trophozoite exported protein 1 (Tex1).
Differential roles of TGIF family genes in mammalian reproduction.
Pask et al., Melbourne, Australia. In Bmc Dev Biol, 2010
Human TGIFLX and its orthologue, Tex1 in the mouse, are X-linked genes that are only expressed in the adult testis.
ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex.
Reed et al., Boston, United States. In Genes Dev, 2010
The conserved TREX mRNA export complex is known to contain UAP56, Aly, Tex1, and the THO complex.
Insights into the organization of dorsal spinal cord pathways from an evolutionarily conserved raldh2 intronic enhancer.
Xavier-Neto et al., São Paulo, Brazil. In Development, 2010
Enhancer activity is directed dorsally to the roof plate and dorsal-most (dI1) interneurons through predicted Tcf- and Cdx-homeodomain binding sites and is repressed ventrally via predicted Tgif homeobox and ventral Lim-homeodomain binding sites.
Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity.
Aguilera et al., Sevilla, Spain. In Mol Genet Genomics, 2008
THO is composed of Tho2, Hpr1, Mft1 and Thp2 subunits, which associate with the Sub2-Yra1 export factors and Tex1 to form the TREX complex.
The 18mer peptaibols from Trichoderma virens elicit plant defence responses.
Kenerley et al., Israel. In Mol Plant Pathol, 2007
Disruption of the NRPS gene, tex1, encoded by a 62.8-kb uninterrupted open reading frame, results in the loss of production of all forms of 18-residue peptaibols.
Recruitment of the human TREX complex to mRNA during splicing.
Reed et al., Boston, United States. In Genes Dev, 2005
recruitment of the human TREX complex to spliced mRNA is not directly coupled to transcription, but is instead coupled to transcription indirectly through splicing
Multiple non-ribosomal peptide synthetase genes determine peptaibol synthesis in Trichoderma virens.
Straney et al., College Park, United States. In Can J Microbiol, 2005
The present study examined the Tex1 homolog in a commercially relevant T. virens strain, G20.
Expression of a novel TGIF subclass homeobox gene, Tex1, in the spermatids of mouse testis during spermatogenesis.
Hsieh-Li et al., Taipei, Taiwan. In Mech Dev, 2002
Tex1 may play a crucial role during mouse spermatogenesis
Meis2, a novel mouse Pbx-related homeobox gene induced by retinoic acid during differentiation of P19 embryonal carcinoma cells.
Dollé et al., Strasbourg, France. In Dev Dyn, 1997
The Meis2 homeodomain is identical to that of Meis1, and is most closely related to those of the Pbx/TGIF homeobox gene products.
Intracellular localization of the PDE4A cAMP-specific phosphodiesterase splice variant RD1 (RNPDE4A1A) in stably transfected human thyroid carcinoma FTC cell lines.
Houslay et al., Glasgow, United Kingdom. In Biochem J, 1997
A similar pattern of labelling was observed using the antiserum Tex1, which specifically identified the Golgi apparatus.
Expression of a novel murine homeobox gene in the developing cerebellar external granular layer during its proliferation.
Clerc et al., Basel, Switzerland. In Dev Dyn, 1996
The TGIF homeobox gene encodes a homeoprotein that represses the 9-cis retinoic acid receptor-dependent transcription activation.
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