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Major facilitator superfamily domain containing 10

TETRAN, Tetracycline transporter-like protein
This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein likely functions in efflux of organic anions, including the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009] (from NCBI)
Top mentioned proteins: HAD, CAN, OUT, STEP, FasT
Papers on TETRAN
Epigenetic silencing of KAZALD1 confers a better prognosis and is associated with malignant transformation/progression in glioma.
Jiang et al., Harbin, China. In Oncol Rep, 2013
Six genes, ADCY1, KAZALD1, KLF4, SLMAP, TETRAN and TP53INP1, were screened out through significance analysis of microarray (SAM), survival Cox-regression and certain other pre-set conditions.
Expression and function of TETRAN, a new type of membrane transporter.
GeneRIF
Mizushima et al., Kumamoto, Japan. In Biochem Biophys Res Commun, 2008
TETRAN is a novel human organic anion transporter, and that it serves as a transporter for some NSAIDs and various other organic anions at the final excretion step.
Identification of the TPO1 gene in yeast, and its human orthologue TETRAN, which cause resistance to NSAIDs.
GeneRIF
Mizushima et al., Kumamoto, Japan. In Febs Lett, 2007
A BLAST search identified the possible human orthologue of Tpo1p, tetracycline transporter-like protein (TETRAN), whose overexpression in cultured human cells caused resistance to some NSAIDs, suggesting that TETRAN is an efflux pump for some NSAIDs.
[Effectiveness of local treatment using a PVP-iodine compound for retained placenta in cows].
Martig et al., Bern, Switzerland. In Berl Munch Tierarztl Wochenschr, 1995
106 cattle with retained placenta were treated either with Vetisept-bolus or Tetran-bolus (controls) after an attempt to remove fetal membranes.
Determination of oxytetracycline and its decomposition products in Tetran vulnerary powder.
Fekete et al., Budapest, Hungary. In Acta Pharm Hung, 1994
A simple and fast HPLC method was developed for the determination of oxytetracycline and its decomposition products in pharmaceutical preparations.
NTP Toxicology and Carcinogenesis Studies of Oxytetracycline Hydrochloride (CAS No. 2058-46-0) in F344/N Rats and B6C3F1 Mice (Feed Studies).
National Toxicology Program, In Natl Toxicol Program Tech Rep Ser, 1987
Synonyms: 2-naphthacenecarboxamide,4(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6-10,2,12a-pentahydroxy-6-methyl-1,11-dioxo-monohydrochloride; Biosolvmycin; Hydrocyclin; Liquamycin; Otetryn; Oxlopar; 5-hydroxytetracycline hydrochloride; Terramycin Hydrochloride; Tetramine; Tetran Hydrochloride
[The role of intrauterine contraceptive devices in the development of inflammatory processes in the small pelvis].
Batar, In Orv Hetil, 1986
Treatment included Semicillin or Tetran, or removal of the IUD, and even surgery if no improvement resulted.
[Acute ulcerative colitis with spontaneous regression. A new side effect of contraceptives?].
Albert et al., In Orv Hetil, 1977
Several medications such as Chlorocid, Tetran, Salazopyrin, Rheopyrin, Streptomycin and Oradexon were administered without any effect.
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