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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Testis derived transcript

Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Mar 2011] (from NCBI)
Top mentioned proteins: CAN, iMpact, HAD, V1a, ACID
Papers using TES antibodies
The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions
Way Michael et al., In The Journal of Cell Biology, 2001
... Tes was amplified by PCR from a human fetal Marathon-Ready cDNA library (BD Biosciences; CLONTECH Laboratories, Inc.) using the ...
Papers on TES
Mobile small RNAs regulate genome-wide DNA methylation.
Ecker et al., Cambridge, United Kingdom. In Proc Natl Acad Sci U S A, Feb 2016
UNASSIGNED: RNA silencing at the transcriptional and posttranscriptional levels regulates endogenous gene expression, controls invading transposable elements (TEs), and protects the cell against viruses.
Role of transposable elements in genomic rearrangement, evolution, gene regulation and epigenetics in primates.
Kim et al., In Genes Genet Syst, Feb 2016
UNASSIGNED: The Human Genome Project revealed that almost half of the human genome consists of transposable elements (TEs), which are also abundant in non-human primates.
Transposable Elements, Polydactyl Proteins, and the Genesis of Human-Specific Transcription Networks.
Trono, Lausanne, Switzerland. In Cold Spring Harb Symp Quant Biol, Feb 2016
UNASSIGNED: Transposable elements (TEs) may account for up to two-thirds of the human genome, and as genomic threats they are subjected to epigenetic control mechanisms engaged from the earliest stages of embryonic development.
The effect of transposable elements on phenotypic variation: insights from plants to humans.
Cao et al., Beijing, China. In Sci China Life Sci, Feb 2016
UNASSIGNED: Transposable elements (TEs), originally discovered in maize as controlling elements, are the main components of most eukaryotic genomes.
Genome-wide characterization of maize small RNA loci and their regulation in the required to maintain repression6-1 (rmr6-1) mutant and long-term abiotic stresses.
Varotto et al., Padova, Italy. In Plant Physiol, Feb 2016
The maize genome has a high number of transposable elements (TEs; almost 85%), some of which spawn abundant sRNAs.
Toxocara canis glycans influence antigen recognition by mouse IgG1 and IgM antibodies.
Wiśniewski et al., In Acta Parasitol, Feb 2016
Native TES and recombinant Toxocara mucins generated in Pichia pastoris yeast as well as their deglycosylated forms were used in ELISA.
The primate-specific noncoding RNA HPAT5 regulates pluripotency during human preimplantation development and nuclear reprogramming.
Reijo Pera et al., Stanford, United States. In Nat Genet, Jan 2016
Long intergenic noncoding RNAs (lincRNAs) are derived from thousands of loci in mammalian genomes and are frequently enriched in transposable elements (TEs).
What makes up plant genomes: The vanishing line between transposable elements and genes.
Jiang et al., East Lansing, United States. In Biochim Biophys Acta, Jan 2016
As the largest component in plant genomes, transposable elements (TEs) create numerous types of mutations that cannot be mimicked by other genetic mechanisms.
The piRNA Pathway Guards the Germline Genome Against Transposable Elements.
Webster et al., Pasadena, United States. In Adv Exp Med Biol, Dec 2015
Transposable elements (TEs) have the capacity to replicate and insert into new genomic locations.
Nomadic genetic elements contribute to oncogenic translocations: Implications in carcinogenesis.
Premkumar et al., Tiruchchirāppalli, India. In Crit Rev Oncol Hematol, Dec 2015
TEs are highly conserved mobile genetic elements that generate DSBs, subsequently resulting in large chromosomal rearrangements.
Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution.
Yu et al., Anyang, China. In Nat Biotechnol, May 2015
Repeated sequences account for 67.2% of the AtDt genome, and transposable elements (TEs) originating from Dt seem more active than from At. Reduction in the AtDt genome size occurred after allopolyploidization.
Transposable elements at the center of the crossroads between embryogenesis, embryonic stem cells, reprogramming, and long non-coding RNAs.
Pei et al., Guangzhou, China. In Sci Bull (beijing), 2014
UNASSIGNED: Transposable elements (TEs) are mobile genomic sequences of DNA capable of autonomous and non-autonomous duplication.
Population genomics of transposable elements in Drosophila.
González et al., Barcelona, Spain. In Annu Rev Genet, 2013
Studies of the population dynamics of transposable elements (TEs) in Drosophila melanogaster indicate that consistent forces are affecting TEs independently of their modes of transposition and regulation.
The contributions of transposable elements to the structure, function, and evolution of plant genomes.
Wang et al., Kunming, China. In Annu Rev Plant Biol, 2013
Transposable elements (TEs) are the key players in generating genomic novelty by a combination of the chromosome rearrangements they cause and the genes that come under their regulatory sway.
Dosage compensation via transposable element mediated rewiring of a regulatory network.
Bachtrog et al., Berkeley, United States. In Science, 2013
Transposable elements (TEs) may contribute to evolutionary innovations through the rewiring of networks by supplying ready-to-use cis regulatory elements.
Comparative gene expression analysis between coronary arteries and internal mammary arteries identifies a role for the TES gene in endothelial cell functions relevant to coronary artery disease.
Wang et al., Cleveland, United States. In Hum Mol Genet, 2012
Low TES gene expression is associated with coronary artery disease.
Prognostic relevance of the expressions of CAV1 and TES genes on 7q31 in melanoma.
Balazs et al., Debrecen, Hungary. In Front Biosci (elite Ed), 2011
Alterations of TES mRNA level may predict the location of metastasis. CAV1 possibly affect the cancer cell invasion
Testin, a novel binding partner of the calcium-sensing receptor, enhances receptor-mediated Rho-kinase signalling.
Ward et al., Australia. In Biochem Biophys Res Commun, 2011
These results suggest an interplay between the CaR and testin in the regulation of CaR-mediated Rho signalling with possible effects on the cytoskeleton.
Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A.
Way et al., London, United Kingdom. In J Biol Chem, 2011
Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A.
Extensive analysis of D7S486 in primary gastric cancer supports TESTIN as a candidate tumor suppressor gene.
Xia et al., Guangzhou, China. In Mol Cancer, 2009
results support the role of TES as a TSG in gastric carcinogenesis and that TES is inactivated primarily by LOH and CpG island methylation
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