The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] (from
Lovejoy et al., Toronto, Canada. In Neuroscience, 2012
Our data provides novel evidence that functionally links the teneurin and dystroglycan systems and provides new insight into the molecular mechanisms by which TCAP-1 regulates cytoskeletal dynamics in hippocampal neurons
Chiquet-Ehrismann et al., Basel, Switzerland. In Bmc Dev Biol, 2010
Data show that human teneurin-1 is directly regulated by EMX2 at a conserved promoter region upstream of the transcription start site, and identify and characterize the EMX2 dependent promoter element of human teneurin-1.
Rotzinger et al., Toronto, Canada. In Behav Brain Res, 2009
TCAP-1 attenuated the corticotropin-releasing factor (CRF)-induced increase in c-Fos expression in the limbic system: TCAP-1 may play a potential role in the stress regulation by blocking CRF-mediated activity in stress-sensitive areas of the brain