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Vestigial like 1

TDU, Vgl-1
The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. [provided by RefSeq, Sep 2009] (from NCBI)
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Top mentioned proteins: TEF, vigilin, Tactile, VITO-1, CAN
Papers on TDU
VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex.
Ji et al., Shanghai, China. In Cell Res, 2014
Our data show that VGLL4 directly competes with YAP in binding to TEADs and executes its growth-inhibitory function through two TDU domains.
Two different vestigial like 4 genes are differentially expressed during Xenopus laevis development.
Tríbulo et al., San Miguel de Tucumán, Argentina. In Int J Dev Biol, 2013
The vestigial gene (vg) was first characterized in Drosophila and several homologues were identified in vertebrates and called vestigial like 1-4 (vgll1-4).
A novel partner of Scalloped regulates Hippo signaling via antagonizing Scalloped-Yorkie activity.
Zhang et al., Shanghai, China. In Cell Res, 2013
Here we identify a novel protein Sd-Binding-Protein (SdBP)/Tgi, which directly competes with Yki for binding to Sd through its TDU domains and inhibits the Sd-Yki transcriptional activity.
Crossmodal recruitment of the ventral visual stream in congenital blindness.
Kupers et al., Montréal, Canada. In Neural Plast, 2011
Congenitally blind and blindfolded sighted control subjects were scanned after they had been trained during four consecutive days to perform a tactile-form recognition task with the tongue display unit (TDU).
Expression of keratin 19, Na-K-Cl cotransporter and estrogen receptor alpha in developing mammary glands of ewes.
Colitti, Udine, Italy. In Histol Histopathol, 2011
In situ hybridization analysis confirmed quantitative data and localized the CK 19 transcript at basal and luminal compartment of terminal ductal unit (TDU) of prepubertal mammary glands.
Neural correlates of virtual route recognition in congenital blindness.
Ptito et al., Copenhagen, Denmark. In Proc Natl Acad Sci U S A, 2010
We first trained congenitally blind and blindfolded sighted control subjects to perform a virtual navigation task with the tongue display unit (TDU), a tactile-to-vision sensory substitution device that translates a visual image into electrotactile stimulation applied to the tongue.
Co-expression of recombinant nucleoside phosphorylase from Escherichia coli and its application.
Ou et al., Shanghai, China. In Appl Biochem Biotechnol, 2009
Two of them had double recombinant plasmids (DUD and DAD) and the other two had tandem recombinant plasmid (TDU and TDA) in them.
A Sveinsson's chorioretinal atrophy-associated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZ.
Kitagawa, Kumamoto, Japan. In Biochem Biophys Res Commun, 2007
The missense mutation reduced the ability of Tead1 to interact with the co-factors YAP and TAZ, but not with the co-factors Vgl-1, -2, and -3, in a mammalian two-hybrid assay.
Guiding the surgical gesture using an electro-tactile stimulus array on the tongue: a feasibility study.
Payan et al., Grenoble, France. In Ieee Trans Biomed Eng, 2007
For this, the sensory substitution paradigm using the Bach-y-Rita's "Tongue Display Unit" (TDU) is exploited to provide to the surgeon information of the position tool.
The transcriptional co-activator TAZ interacts differentially with transcriptional enhancer factor-1 (TEF-1) family members.
Farrance et al., Baltimore, United States. In Biochem J, 2005
TEF-1 activity is regulated by interactions with transcriptional co-factors [p160, TONDU (Vgl-1, Vestigial-like protein-1), Vgl-2 and YAP65 (Yes-associated protein 65 kDa)].
Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes.
Stewart et al., Pittsburgh, United States. In J Biol Chem, 2004
Unlike other members of the Vgl family that have a single TEF-1 interaction domain called the tondu (TDU) motif, Vgl-4 has two TDU motifs in its carboxyl-terminal domain.
Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2 transcription factors that promotes skeletal muscle differentiation.
Stewart et al., Pittsburgh, United States. In J Biol Chem, 2003
Here, we identify three mammalian vestigial-like genes, Vgl-1, Vgl-2, and Vgl-3, that share homology in a TEF-1 interaction domain.
Nitric oxide synthase inhibition attenuates vasoactive response to spinal cord stimulation in an experimental cerebral vasospasm model.
Oztoprak et al., Sivas, Turkey. In Acta Neurochir (wien), 2000
METHOD: Four experimental groups, were designated: Group 1. Cerebral blood flow (CBF) was evaluated by transcranial Doppler ultrasonography (TDU) in 8 rabbits.
TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation.
Zider et al., France. In Development, 1999
We also identify a novel human protein, TONDU, which contains a short domain homologous to the domain of Vg required for interaction with Sd.
UMP synthase activity expressed in deficient hamster cells by separate transferase and decarboxylase proteins or by linker-deleted bifunctional protein.
Suttle et al., Memphis, United States. In Somat Cell Mol Genet, 1995
Transfected Urd-C cells surviving selection in media without added uridine were isolated and designated transferase decarboxylase Urd-C (TDU).
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