Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress
In The Journal of Cell Biology, 1997
... For stable transfection, Rat-1/Wnt-1 cells were cotransfected with pcDNA3-flag-DN-Tcf-4, encoding the dominant-negative mutant (DN) of Tcf-4, or control empty vector and pBabe vector, containing a puromycin selectable marker, with Superfect (QIAGEN), according to the manufacturer's ...
Plakophilins in desmosomal adhesion and signaling.
Halle, Germany. In Cell Commun Adhes, Feb 2014
β-catenin (armadillo in Drosophila) is the prototype of a multifunctional molecule that regulates cell adhesion via adherens junctions and cell signaling via LEF/TCF transcription factors.
Insulin gene mutations and diabetes.
Wakayama, Japan. In J Diabetes Investig, 2011
Maturity-onset diabetes of the young (MODY) or an autoantibody-negative type 1-like phenotype has also been reported.