Genome Wide Association Analysis Reveals New Production Trait Genes in a Male Duroc Population.
Beijing, China. In Plos One, 2014
The Gene ontology analysis identified 14 candidate genes close to significant single nucleotide polymorphisms, with growth-related functions: six for days to 100 KG (WT1, FBXO3, DOCK7, PPP3CA, AGPAT9, and NKX6-1), seven for food conversion ratio (MAP2, TBX15, IVL, ARL15, CPS1, VWC2L, and VAV3), and one for average daily gain (COL27A1).
Multi-ethnic fine-mapping of 14 central adiposity loci.
Chapel Hill, United States. In Hum Mol Genet, 2014
Trans-ethnic analyses at five loci (TBX15-WARS2, LYPLAL1, ADAMTS9, LY86 and ITPR2-SSPN) substantially narrowed the signals to smaller sets of variants, some of which are in regions that have evidence of regulatory activity.
The genetics of fat distribution.
Leipzig, Germany. In Diabetologia, 2014
Indeed, genes such as TBX15 not only manifest differential expression in various fat depots, but also correlate with obesity and related traits.
Effect of maternal methionine supplementation on the transcriptome of bovine preimplantation embryos.
Madison, United States. In Plos One, 2012
Interestingly, several of the most significant genes are related to embryonic development (e.g., VIM, IFI6, BCL2A1, and TBX15) and immune response (e.g., NKG7, TYROBP, SLAMF7, LCP1, and BLA-DQB).
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
Regensburg, Germany. In Nat Genet, 2010
We identified 13 new loci in or near RSPO3, VEGFA, TBX15-WARS2, NFE2L3, GRB14, DNM3-PIGC, ITPR2-SSPN, LY86, HOXC13, ADAMTS9, ZNRF3-KREMEN1, NISCH-STAB1 and CPEB4 (P = 1.9 × 10⁻⁹ to P = 1.8 × 10⁻⁴⁰) and the known signal at LYPLAL1.