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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

TBC1

TBC
TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).[supplied by OMIM, Mar 2008] (from NCBI)
Papers on TBC
Exercise increases TBC1D1 phosphorylation in human skeletal muscle.
GeneRIF
Goodyear et al., Boston, United States. In Am J Physiol Endocrinol Metab, 2011
A single bout of exercise regulates TBC1D1 and AS160 phosphorylation on multiple sites in human skeletal muscle.
Crystal structures of human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating protein (RabGAP) domains reveal critical elements for GLUT4 translocation.
GeneRIF
Shoelson et al., Boston, United States. In J Biol Chem, 2011
Crystal structures of human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating protein (RabGAP) domains reveal critical elements for GLUT4 translocation.
Exercise-induced TBC1D1 Ser237 phosphorylation and 14-3-3 protein binding capacity in human skeletal muscle.
GeneRIF
Wojtaszewski et al., Copenhagen, Denmark. In J Physiol, 2010
TBC1D1 is Ser237 phosphorylated and binding capacity to 14-3-3 protein is increased in skeletal muscle following exercise.
Of mice and men: filling gaps in the TBC1D1 story.
GeneRIF
Cartee, Ann Arbor, United States. In J Physiol, 2010
[review] The question of a mechanism for increased phosphorylation of Ser237-TBC1D1 after exercise has, so far, not had a straightforward experimental approach for a direct answer in humans undergoing in vivo exercise.
R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population.
GeneRIF
Froguel et al., Lille, France. In Hum Mol Genet, 2008
These results confirm a putative role of TBC1D1 R125W variant in familial obesity predisposition.
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