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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Transmembrane anterior posterior transformation 1

Tapt1, CMVFR
This gene encodes a highly conserved, putative transmembrane protein. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. This gene is proposed to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. An alternatively spliced transcript variant encoding a substantially different isoform has been described, but its biological validity has not been determined. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Hoxc9, Orf, SIMPLE, AGE, GGA3
Papers on Tapt1
Genetic Defects in TAPT1 Disrupt Ciliogenesis and Cause a Complex Lethal Osteochondrodysplasia.
Coucke et al., Gent, Belgium. In Am J Hum Genet, Nov 2015
The evolutionarily conserved transmembrane anterior posterior transformation 1 protein, encoded by TAPT1, is involved in murine axial skeletal patterning, but its cellular function remains unknown.
Genome-wide association study identifies Loci and candidate genes for body composition and meat quality traits in Beijing-You chickens.
Wen et al., Beijing, China. In Plos One, 2012
A consistent region on chicken (Gallus gallus) chromosome 4 (GGA4), including seven significant SNPs and four candidate genes (LCORL, LAP3, LDB2, TAPT1), were found to be associated with CW and EW.
Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations.
Schimenti et al., Bar Harbor, United States. In Genetics, 2007
A perinatal lethal mutation in mouse Tapt1 results in homeotic, posterior-to-anterior transformations of the axial skeleton.
Cloning and epitope mapping of a functional partial fusion receptor for human cytomegalovirus gH.
Keay et al., Baltimore, United States. In J Gen Virol, 2000
A cDNA clone encoding a partial putative human cytomegalovirus (HCMV) gH fusion receptor (CMVFR) was previously identified.
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