gopubmed logo
 
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 24 Oct 2014.

GRP1

tamalin, GRP1-associated scaffold protein
scaffold protein; promotes intracellular trafficking and cell surface expression of group 1 metabotropic glutamate receptors [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: GRP1, ACID, MAGI-2, ARNO, metabotropic glutamate receptor
Papers on tamalin
Support for the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia from exome sequencing in multiplex families.
New
Tsuang et al., Seattle, United States. In Jama Psychiatry, Jun 2013
One pedigree shared a missense and frameshift substitution of GRM5, encoding the metabotropic glutamate receptor subtype 5 (mGluR5), which is coupled to the NMDA receptor and potentiates its signaling; the frameshift disrupts binding to the scaffolding protein tamalin and increases mGluR5 internalization.
Grp1 plays a key role in linking insulin signaling to glut4 recycling.
GeneRIF
Hsu et al., Boston, United States. In Dev Cell, 2012
A major mechanism by which insulin regulates glut4 recycling was uncovered. A general receptor for 3-phosphoinositides 1 was identified as a guanine nucleotide exchange factor for ADP-ribosylation factor 6 that promotes glut4 vesicle formation.
Allosteric regulation of GRASP protein-dependent Golgi membrane tethering by mitotic phosphorylation.
GeneRIF
Linstedt et al., Pittsburgh, United States. In J Biol Chem, 2012
the structural basis of the phosphoinhibition of GRASP-mediated membrane tethering and provide a mechanism for its allosteric regulation.
PDZ-scaffold protein, Tamalin promotes dendritic outgrowth and arborization in rat hippocampal neuron.
GeneRIF
Kim et al., Seoul, South Korea. In Biochem Biophys Res Commun, 2012
These results suggest that Tamalin is responsible for neuronal dendritic development via regulation of EFA6A/Arf6-mediated cytoskeleton dynamics.
Tamalin is a critical mediator of electroconvulsive shock-induced adult neuroplasticity.
GeneRIF
Tessarollo et al., Frederick, United States. In J Neurosci, 2012
An upregulation of scaffold protein tamalin is found selectively in the hippocampus of animals subjected to electroconvulsive shock.
GRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180.
GeneRIF
Santy et al., United States. In Mol Biol Cell, 2010
protein-protein interaction mediated by ARNO coiled-coil domain required for ARNO induced motility; coiled-coil domain promotes assembly of multiprotein complex containing ARNO and Dock180; assembly of complex requires coiled-coil domain, GRASP and IPCEF
Altered sensitivities to morphine and cocaine in scaffold protein tamalin knockout mice.
Nakanishi et al., Suita, Japan. In Proc Natl Acad Sci U S A, 2007
Tamalin is a scaffold protein that interacts with metabotropic glutamate receptors and the kinase-deficient neurotrophin TrkCT1 receptor and forms a protein complex with multiple protein-trafficking and intracellular signaling molecules.
A kinase-deficient TrkC receptor isoform activates Arf6-Rac1 signaling through the scaffold protein tamalin.
Tessarollo et al., Frederick, United States. In J Cell Biol, 2006
We show that the neurotrophin-3 (NT3) TrkCT1-truncated receptor binds to the scaffold protein tamalin in a ligand-dependent manner.
Phosphorylation and recruitment of Syk by immunoreceptor tyrosine-based activation motif-based phosphorylation of tamalin.
GeneRIF
Nakanishi et al., Kyoto, Japan. In J Biol Chem, 2004
tamalin is a novel signaling molecule that possesses a PDZ domain and a PDZ binding motif and mediates Syk signaling in an ITAM-based fashion
Hyperpolarization-activated, cyclic nucleotide-gated HCN2 cation channel forms a protein assembly with multiple neuronal scaffold proteins in distinct modes of protein-protein interaction.
Nakanishi et al., Kyoto, Japan. In Genes Cells, 2004
In this investigation, we report that HCN2 forms a protein assembly with tamalin, S-SCAM and Mint2 scaffold proteins, using several different approaches including immunoprecipitation of rat brain and heterologously expressing cell extracts and glutathione S-transferase pull-down assays.
Tamalin is a scaffold protein that interacts with multiple neuronal proteins in distinct modes of protein-protein association.
GeneRIF
Nakanishi et al., Kyoto, Japan. In J Biol Chem, 2003
Tamalin interacts with multiple neuronal proteins and several scaffold proteins in the brain through its distinct evolutionarily-conserved protein-binding domains; and tamalin mRNA is developmentally up-regulated at the postnatal period.
Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins.
Nakanishi et al., Kyoto, Japan. In J Neurosci, 2002
In this investigation, we report identification and characterization of a 95 kDa postsynaptic density protein (PSD-95)/discs-large/ZO-1 (PDZ) domain-containing protein termed tamalin, also recently named GRP1-associated scaffold protein (GRASP), that interacts with group 1 metabotropic glutamate receptors (mGluRs).
Interaction of GRASP, a protein encoded by a novel retinoic acid-induced gene, with members of the cytohesin family of guanine nucleotide exchange factors.
Leid et al., Corvallis, United States. In J Biol Chem, 2000
A novel, retinoic acid-induced gene, GRP1-associated scaffold protein (GRASP), was isolated from P19 embryonal carcinoma cells using a subtractive screening strategy.
share on facebooktweetadd +1mail to friends