Treatment of Ebola virus infections with inhibitors of TLR4.
Berlin, Germany. In Med Hypotheses, 15 Jun 2015
As evidence suggests that GP1,2 and LPS use the same receptor, it is tempting to evaluate whether compounds that can inhibit signal transduction by LPS, e.g., TAK-242, can also reduce EBOV-induced pathogenesis.
Endothelin Receptors and Their Antagonists.
Cambridge, United Kingdom. In Semin Nephrol, Mar 2015
The role of the two receptors has been delineated using highly selective ETA (BQ123, TAK-044) and ETB (BQ788) peptide antagonists.
Recent advances in Takayasu arteritis.
Kyoto, Japan. In Int J Rheum Dis, Mar 2014
Takayasu arteritis (TAK) is a relatively rare systemic vasculitis mainly affecting the aorta and its large branches.