Screening of kinase inhibitors targeting BRAF for regulating autophagy based on kinase pathways.
Harbin, China. In Mol Med Report, 31 Jan 2014
Previous studies indicated that sorafenib is capable of regulating autophagy and regorafenib has also been reported; however, there have been no studies regarding the regulation of autophagy by afatinib, selumetinib, PD318088, axitinib, TAK-733, GDC-0980, GSK2126458, PLX-4720, AS703026, trametinib, GDC-0941 and PF-04217903.
Efficacy and toxicity of factor Xa inhibitors.
Marseille, France. In J Pharm Pharm Sci, Dec 2012
New antithrombotics such as rivaroxaban, apixaban, betrixaban, edoxaban, darexaban, TAK-442, LY517717, eribaxaban, otamixaban are being developed to overcome current therapeutic limitations.