Assessment of the presence of chemosensing receptors based on bitter and fat taste in the gastrointestinal tract of young pig.
Reggio nell'Emilia, Italy. In J Anim Sci, 2012
For 7 genes for bitter taste (TAS2R1, TAS2R3, TAS2R7, TAS2R9, TAS2R10, TAS2R16, and TAS2R38) and for 3 genes for fat taste (GPR40, GPR43, and GPR120), a full homology for exon sequences was found and primers were designed by Primer3.
Bitter taste receptor T2R1 is activated by dipeptides and tripeptides.
Winnipeg, Canada. In Biochem Biophys Res Commun, 2010
The ligand binding pocket in T2R1 is present on the extracellular surface of the receptor, and is formed by the transmembrane helices 1, 2, 3 and 7 and with extracellular loops 1 and 2 forming a cap like structure on the binding pocket.