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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Syntaxin 7

syntaxin 7, syn-7, STX7
Top mentioned proteins: v-SNARE, VAMP8, ACID, V1a, HAD
Papers on syntaxin 7
Munc13-4 interacts with syntaxin 7, regulates late endosomal maturation, endosomal signaling and TLR9-initiated cellular responses.
Catz et al., San Diego, United States. In Mol Biol Cell, Jan 2016
Here, we identify a novel mechanism of late endosomal maturation that involves a new molecular interaction between the tethering factor Munc13-4, syntaxin 7 and VAMP8.
Mosaic parental germline mutations causing recurrent forms of malformations of cortical development.
Chelly et al., Paris, France. In Eur J Hum Genet, Oct 2015
Interestingly, four families with parental germline variants, out of 18, were identified by whole-exome sequencing (WES), including a variant in a new candidate gene, syntaxin 7.
γ-SNAP stimulates disassembly of endosomal SNARE complexes and regulates endocytic trafficking pathways.
Tagaya et al., Hachiōji, Japan. In J Cell Sci, Sep 2015
γ-SNAP, as well as α-SNAP, mediated the disassembly of endosomal syntaxin-7-containing SNARE complexes.
Contact Toxicity and Repellency of the Essential Oil of Dictamnus dasycarpus Roots from China against Two Stored-Product Insects.
Deng et al., Puerto Rico. In Chem Biodivers, Jun 2015
The essential oil obtained by hydrodistillation of D. dasycarpus roots was characterized by GC-FID and GC/MS analyses, and the main components identified were syn-7-hydroxy-7-anisylnorbornene (1, 49.9%), 1,3,4,5,6,7-hexahydro-2H-inden-2-one (2, 11.6%), 5,6-diethenyl-1-methylcyclohexene (3, 7.4%), and 3,9-dimethyltricyclo[,5)]dec-3-en-9-ol
Synthesis of a Tight Intramolecular OH···Olefin Interaction, Probed by IR, (1)H NMR, and Quantum Chemistry.
Lectka et al., Baltimore, United States. In J Org Chem, Jun 2015
The interaction is notable in that it possesses a better defined intramolecular hydrogen bond compared to the usual molecules for which it is noted, such as syn-7-norbornenol.
UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs.
Liang et al., Los Angeles, United States. In Proc Natl Acad Sci U S A, 2014
UVRAG mediates viral endocytic transport and membrane penetration through interactions with the class C vacuolar protein sorting (C-Vps) tethering complex and endosomal glutamine-containing SNAREs [syntaxin 7 (STX7), STX8, and vesicle transport through t-SNARE homolog 1B (Vti1b)], leading to the assembly of a fusogenic trans-SNARE complex involving vesicle-associated membrane protein (VAMP8), but not VAMP7.
Nucleophilic substitution of bromonorbornenes and derivatives by electron transfer reactions.
Pierini et al., Córdoba, Argentina. In Org Biomol Chem, 2013
The photoinitiated substitution reactions of anti-7-bromobenzonorbornadiene (5), its syn isomer 6, exo-anti-13-bromobenzocyclobutanorbornene (7), syn-7-bromonorbornene (8) and bromonorbornane (9) with Me(3)Sn(-) and Ph(2)P(-) anions, in liquid ammonia, are here informed to occur with good yields of substitution.
An approach to aliphatic 1,8-stereocontrol: diastereoselective syntheses of (±)-patulolide C and (±)-epipatulolide C.
Thomas et al., Manchester, United Kingdom. In Org Biomol Chem, 2012
The tin(iv) bromide promoted reaction of 7-hydroxy-7-phenylhept-2-enyl(tributyl)stannane 11 with benzaldehyde gave a mixture of the epimeric 1,8-diphenyloct-3-ene-1,8-diols 12 and so indirect methods were developed for aliphatic 1,8-stereocontrol to complete diastereoselective syntheses of (±)-patulolide C 1 and (±)-epipatulolide C 40. (5Z)-3,7-syn-7-(2-Trimethylsilylethoxy)methoxyocta-1,5-dien-3-ol 17 was prepared from the tin(iv) chloride promoted reaction of 4-(2-trimethylsilylethoxy)methoxypent-2-enyl(tributyl)stannane 16 with acrolein (1,5-syn : 1,5-anti = 96 : 4).
SNARE protein expression and localization in human cytotoxic T lymphocytes.
Hoth et al., Homburg, Germany. In Eur J Immunol, 2012
Vti1b, Stx8 and Stx16 had the highest degrees of co-localization with LGs while Stx3, Stx4, Stx6, Stx7, Stx8, Stx13, Vti1b, VAMP3 and VAMP4 co-localized with CD3.
Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytes.
Rettig et al., Homburg, Germany. In Traffic, 2011
Data suggest that accumulation of recycling T cell receptors at the immunological synapse is SNARE-dependent and that Stx7-mediated processing of recycling TCRs through endosomes is a prerequisite for the cytolytic function of cytotoxic T lymphocytes.
Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages.
Murray et al., Brisbane, Australia. In Traffic, 2011
While Stx11 did not form a typical trans-SNARE complex, it did bind to the Q-SNARE Vti1b and was able to regulate the availability of Vti1b to form the Q-SNARE complexes Stx6/Stx7/Vtib and Stx7/Stx8/Vti1b.
The cystic fibrosis transmembrane conductance regulator's expanding SNARE interactome.
Lee et al., Singapore, Singapore. In Traffic, 2011
Members of the STX8/STX7/vesicle transport through interaction with t-SNAREs homolog 1b/VAMP8 SNARE complex, which function in early to late endosome/lysosome traffic, are all known to interact with CFTR.
Intracellular location of syntaxin 7 in human neutrophils.
Mollinedo et al., Salamanca, Spain. In Immunol Lett, 2010
data reveal the presence of syntaxin 7 in the membranes of exocytosis-prone granules and phagocytosis-related granules in human neutrophils, and therefore it might play a role in both exocytosis and phagocytosis in human neutrophils
Selective expression of Syntaxin-7 protein in benign melanocytes and malignant melanoma.
Ponten et al., Uppsala, Sweden. In J Proteome Res, 2009
The expression level of STX7 protein was inversely correlated to tumor stage, suggesting that decreased expression of STX7 is associated with more aggressive tumors.
Differential palmitoylation of the endosomal SNAREs syntaxin 7 and syntaxin 8.
Linder et al., Saint Louis, United States. In J Lipid Res, 2009
Palmitoylation-defective syntaxin 7 is selectively retained on the plasma membrane, suggesting that palmitoylation is important for intercompartmental transport of syntaxin 7.
Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factor 1 in macrophages.
Scholz et al., Melbourne, Australia. In Mol Cell Biol, 2008
Colony-stimulating factor 1 is a key regulator of Stx7 expression and function in macrophages.
Relationship between endosomes and lysosomes.
Piper et al., Cambridge, United Kingdom. In Biochem Soc Trans, 2001
It requires syntaxin 7 as part of the functional trans-SNARE [SNAP receptor, where SNAP is soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein] complex and the release of lumenal calcium to achieve membrane fusion.
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