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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Synergin, gamma

Syng
This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on Syng
Aftiphilin and gamma-synergin are required for secretagogue sensitivity of Weibel-Palade bodies in endothelial cells.
GeneRIF
Cutler et al., London, United Kingdom. In Mol Biol Cell, 2008
Data show that by recruiting aftiphilin/gamma-synergin in addition to clathrin, AP-1 coordinates formation of Weibel-Palade bodies with their acquisition of a regulated secretory phenotype.
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes.
GeneRIF
Raposo et al., Cambridge, United Kingdom. In Mol Biol Cell, 2005
AP-3 and AP-1 function in partially redundant pathways to transfer tyrosinase from distinct endosomal subdomains to melanosomes
The aftiphilin/p200/gamma-synergin complex.
GeneRIF
Robinson et al., Cambridge, United Kingdom. In Mol Biol Cell, 2005
the aftiphilin/p200/gamma-synergin complex facilitates AP-1 function
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