In Retrovirology, 1991
... Anti-ESET(SETDB1) and anti-SUV39H1 antibodies were purchased from Cell Signaling (Danvers, MA) ...
Stem Cell Depletion by Global Disorganization of the H3K9me3 Epigenetic Marker in Aging.
Sunnyvale, United States. In Rejuvenation Res, Aug 2015
Although WRN plays a role in DNA repair, WRN exerted its effects on aging via maintaining heterochromatin, evidenced by reduced levels of interacting chromatin regulators heterochromatin protein 1α (HP1α), suppressor of variegation 3-9 homolog 1 (SUV39H1), and lamina-associated polypeptide 2β (LAP2β) as well as modified histone H3K9me3.
Multiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4).
Oxford, United Kingdom. In Mol Cell Endocrinol, 2014
Thus, menin by forming a subunit of the mixed lineage leukemia (MLL) complexes that trimethylate histone H3 at lysine 4 (H3K4), facilitates activation of transcriptional activity in target genes such as cyclin-dependent kinase (CDK) inhibitors; and by interacting with the suppressor of variegation 3-9 homolog family protein (SUV39H1) to mediate H3K methylation, thereby silencing transcriptional activity of target genes.
Epigenetic regulation of EMT: the Snail story.
Lexington, United States. In Curr Pharm Des, 2013
Histone deacetylation may promote subsequent recruitment of PRC2 to methylate H3K27, while H3K4 demethylation favors the association of H3K9 methyltransferases G9a and Suv39H1.