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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Ubiquitin associated and SH3 domain containing, A

Sts-2
Top mentioned proteins: EGFR, Tula, Cbl, Syk, ZAP-70
Papers on Sts-2
Protection from systemic Candida albicans infection by inactivation of the Sts phosphatases.
New
Carpino et al., Stony Brook, United States. In Infect Immun, Feb 2015
The suppressor of TCR signaling 1 (Sts-1) and Sts-2 are two homologous phosphatases that negatively regulate signaling pathways in a number of hematopoietic cell lineages, including T lymphocytes, mast cells, and platelets.
Enhanced response of T cells from murine gammaherpesvirus 68-infected mice lacking the suppressor of T cell receptor signaling molecules Sts-1 and Sts-2.
Krug et al., Stony Brook, United States. In Plos One, 2013
However, these alterations in the immune response and the overall absence of Sts-1 and Sts-2 did not impact viral pathogenesis or lead to pathology.
New insights into the catalytic mechanism of histidine phosphatases revealed by a functionally essential arginine residue within the active site of the Sts phosphatases.
Carpino et al., Stony Brook, United States. In Biochem J, 2013
Sts (suppressor of T-cell receptor signalling)-1 and Sts-2 are HPs (histidine phosphatases) that negatively regulate TCR (T-cell receptor) signalling pathways, including those involved in cytokine production.
Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways.
GeneRIF
Carpino et al., Stony Brook, United States. In J Biol Chem, 2011
Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways.
Determination of the substrate specificity of protein-tyrosine phosphatase TULA-2 and identification of Syk as a TULA-2 substrate.
Pei et al., Columbus, United States. In J Biol Chem, 2010
TULA-1 (UBASH3A/STS-2) and TULA-2 (p70/STS-1) represent a novel class of protein-tyrosine phosphatases.
Construct development: The Suicide Trigger Scale (STS-2), a measure of a hypothesized suicide trigger state.
Galynker et al., New York City, United States. In Bmc Psychiatry, 2009
BACKGROUND: This study aims to develop the construct of a 'suicide trigger state' by exploring data gathered with a novel psychometric self-report instrument, the STS-2.
The Sts proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathways.
GeneRIF
Oh et al., Stony Brook, United States. In Mol Immunol, 2009
The Sts-1,2 proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathways.
Structures of the phosphorylated and VO(3)-bound 2H-phosphatase domain of Sts-2.
GeneRIF
Nassar et al., Stony Brook, United States. In Biochemistry, 2009
the crystal structure of Sts-2(PGM) in the phosphorylated active form and bound to VO(3)
TULA-family proteins: an odd couple.
Review
Tsygankov, Philadelphia, United States. In Cell Mol Life Sci, 2009
Two members of the TULA family (TULA/STS-2/UBASH3A and TULA-2/STS-1/UBASH3B) recently emerged as novel regulators of several cellular functions.
Structural and functional characterization of the 2H-phosphatase domain of Sts-2 reveals an acid-dependent phosphatase activity.
GeneRIF
Nassar et al., Stony Brook, United States. In Biochemistry, 2009
Sts-2(phosphoglycerate mutase) adopts the conformation of an active phosphatase whose activity is fundamentally different from that of Sts-1 despite the strong structural homology.
TULA proteins regulate activity of the protein tyrosine kinase Syk.
Tsygankov et al., Philadelphia, United States. In J Cell Biochem, 2008
TULA belongs to a two-member family: TULA (STS-2) is a lymphoid protein, whereas STS-1/TULA-2 is expressed ubiquitously.
Suppressor of T-cell receptor signalling 1 and 2 differentially regulate endocytosis and signalling of receptor tyrosine kinases.
Hoeller et al., Frankfurt am Main, Germany. In Febs Lett, 2007
The UBA domain of Sts-2 and SH3-dependent Cbl-binding are required for this function.
Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases.
Dikic et al., Frankfurt am Main, Germany. In J Biol Chem, 2004
Herein, we describe the identification of two novel Cbl-interacting proteins, p70 and Clip4 (recently assigned the names Sts-1 and Sts-2, respectively), that inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.
Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2.
Impact
Ihle et al., Memphis, United States. In Immunity, 2004
Herein, we describe two related proteins, Sts-1 and Sts-2, that negatively regulate TCR signaling.
Optical contamination measurements on early Shuttle missions.
Owens et al., In Appl Opt, 1988
Two camera/photometers were included as part of the Induced Environment Contamination Monitor on STS-2, -3, -4, and -9 orbital missions to record photographically Shuttle-induced particulate and background contamination.
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